Solitary Extramedullary Plasmacytoma of the Larynx Presenting with Stridor as a Primary Manifestation

H. Al Saey; A. Larem; M. Al Sulaiti; S. Ganesan; I.B. Mujeeb; V. Bhat

doi:10.5339/qmj.2011.2.16

ISSN: 0253-8253
EISSN: 2227-0426

oa Solitary Extramedullary Plasmacytoma of the Larynx Presenting with Stridor as a Primary Manifestation
Authors: H. Al Saey¹, A. Larem¹, M. Al Sulaiti¹, S. Ganesan¹, I.B. Mujeeb² and V. Bhat³
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Affiliations: ¹ ^*ORL-HNS Section, Department of Surgery ² ^**Departments of Laboratory Medicine and Pathology ³ ^***Radiology Hamad Medical Corporation, Doha, Qatar
Source: Qatar Medical Journal, Volume 2011, Issue 2, Dec 2011, 16
DOI: https://doi.org/10.5339/qmj.2011.2.16
- Published online: 01 December 2011

Abstract

More than 90% of malignant tumors of the larynx are squamous cell carcinomas. Extramedullary plasmacytoma is a plasma cell tumour representing less than 1 % of all head and neck malignancies and involvement of the larynx is very rare. In the larynx the supraglottis is the primary site of involvement compared to the glottic and subglottic regions. We report a case of 54-yearold Indonesian female who presented at our clinic with stridor as primary manifestation secondary to solitary extramedullar plasmacytoma involving the glottis and subglottis of the larynx. The patient underwent microlaryngoscopy, biopsy and CO² laser excision of the tumour with significant improvement of the airway and was referred for locoregional radiotherapy. We review the literature and discuss the management of this rare condition.

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2011-12-01

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References

Galieni P, Cavo M, Pulsoni A. Clinical outcome of extramedullary plasmacytoma. Hematologica. 2000; 85::47–51.
[Google Scholar]
Rodriguez-deVelasquez A, Weber AL, Montgomery W. Extramedullary laryngeal plasmacytoma. Ann Otol Rhinol Laryngol. 1996; 105::483–486.
[Google Scholar]
Alexiou C, Kau RJ, Dietzfelbinger H. Extramedullary plasmacytoma: Tumor occurrence and therapeutic concepts. Cancer. 1999; 85::2305–2314.
[Google Scholar]
Maheshwari GK, Gopal U, Shah NM. Extramedullary plasma of the larynx: A case report. J Indian Med Asso. 2001; 99:5:267–268.
[Google Scholar]
Maniglia AJ, Xue JW. Plasmacytoma of the larynx. Laryngoscope. 1983; 93::741–744.
[Google Scholar]
Sakiyama S, Kondo K, Mitsuteru Y. Extramedullary plasmacytoma immunoglobulin D(?) in the chest wall and the subglottic region. J Thorac Cardiovasc Surg. 2005; 129::1168–1169.
[Google Scholar]
Weissmari JL, Myers JN, Kapadia SB. Extramedullary plasmacytoma of the larynx. Am J Otolaryngol. 1993; 14::128–131.
[Google Scholar]

/content/journals/10.5339/qmj.2011.2.16

Article Type: Case Report

Keyword(s): Extramedullary plasmacytoma larynx, multiple myeloma, radiotherapy and stridor

oa Solitary Extramedullary Plasmacytoma of the Larynx Presenting with Stridor as a Primary Manifestation

Abstract

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