1887
Volume 2011, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

There is a growing awareness that Vitamin D sufficiency is required for optimal health during all stages of life. Inadequate Vitamin D status is increasingly recognized as common problem. To assess the serum level of 25 Hydroxyvitamin D 250 HD among healthy post-menopausal Qatari women living in Doha a crosssection randomized study of 205 post-menopausal Qatari women was conducted between 1 September 2008 and 31 April 2009 at four Primary Health Care Centers. Using interviews, a questionnaire, and a 5 ml blood sample, personal data was collected plus likely risk factors for Vitamin D insufficiency. More than onethird of the women (38.0%) had severe Vitamin D deficiency, almost half (47.3%) had mild Vitamin D deficiency, only 14.6% had a normal Vitamin D level. Risk factors were inadequate exposure to the sun, the use of sun screen, complete covering of the body with clothing, low dietary Vitamin D intake and the use of Vitamin D supplements. The study indicated clearly that hypovitaminosis D is common in post-menopausal Qatari women and that efforts are required to encourage adequate exposure to sunlight and an increased intake of fortified Vitamin D to maintain normal levels.

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2011-12-01
2019-10-19
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References

  1. [1]. Rojakumar   K. . Vitamin D, cod-liver oil, sunlight, and rickets: A historical perspective. . Pediatrics . 2003; ;112: : e132– e135 .
    [Google Scholar]
  2. [2]. Garland   CF., , Garland   FC. . Do sunlight and vitamin D reduce the likelihood of colon cancer?.   Int J Epidemiol . 1980; ;9: : 227– 231 .
    [Google Scholar]
  3. [3]. Garland   C., , Shekelle   RB., , Barrett-Connor   E. . Dietary vitamin D and calcium and risk of colorectal cancer: A 19-year prospective study in men. . Lancet . 1985; ;1: : 307– 309 .
    [Google Scholar]
  4. [4]. Grant   WB. . An estimate of premature cancer mortality in the US due to inadequate doses of solar ultraviolet-B radiation. . Cancer . 2002; ;94: : 1867– 1875 .
    [Google Scholar]
  5. [5]. Goldberg   P., , Fleming   MC., , Picard   EH. . Multiple sclerosis: Decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. . Med Hypotheses . 1986; ;21: : 193– 200 .
    [Google Scholar]
  6. [6]. Hayes   CE., , Cantorna   MT., , DeLuca   HE. . Vitamin D and multiple sclerosis. . Proc Soc Exp Biol Med . 1997; ;216: : 21– 27 .
    [Google Scholar]
  7. [7]. Hypponen   E., , Laara   E., , Reunanen   A. . Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. . Lancet . 2001; ;358: : 1500– 1503 .
    [Google Scholar]
  8. [8]. Holick   MF. . The photobiology of vitamin D and its consequences for humans. . Ann NY Acad Sci . 1985; ;453: : 1– 13 .
    [Google Scholar]
  9. [9]. Holick   MF. . Environmental factors that influence the cutaneous production of vitamin D. . Am J Clin Nutr . 1995; ;61: : 638S– 645S .
    [Google Scholar]
  10. [10]. Holick   MF. . Photosynthesis of vitamin D in the skin: Effect of environmental and life-style variables. . Fed Proc . 1987; ;46: : 1876– 1882 .
    [Google Scholar]
  11. [11]. Holick   MF. . Vitamin D and bone health. . J Nutr . 1996; ;126: : 1159S– 1164S .
    [Google Scholar]
  12. [12]. Nesby-O'Dell   S., , Scanlon   KS., , Cogswell   ME., , Gillespie   C., , Hoilis   BW., , Looker   AC. . Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: Third national health and nutrition examination survey, 1988-1994. . Am J Clin Nutr . 2002; ;76: : 187– 192 .
    [Google Scholar]
  13. [13]. Chapuy   MC., , Schott   AM., , Garnero   P., , Hans   D., , Delmas   PD., , Meunier   J., , Group   ES. . Healthy elderly French women living at home have secondary hyperparathyroidism and high bone turnover in winter. . J Clin Endocrinol Metab . 1996; ;81: : 1129– 1133 .
    [Google Scholar]
  14. [14]. Chel   VGM., , Ooms   ME., , Popp-Snijders   C., , Pavel   S., , Schothorst   AA., , Meulemans   CCE., , Lips   P. . Ultraviolet irradiation corrects vitamin D deficiency and suppresses secondary hyperparathyroidism in the elderly. . J Bone Miner Res . 1998; ;13: : 1238– 1242 .
    [Google Scholar]
  15. [15]. Glerup   H., , Mikkelsen   K., , Poulsen   L., , Hass   E., , Overbeck   S., , Thomesen   J., , Charles   P., , Eriksen   EF. . Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited. . J Intern Med . 2000; ;247: : 260– 268 .
    [Google Scholar]
  16. [16]. Gloth   EM., , Gundberg   CM., , Hollis   BW., , Haddad   HG., , Tobin   JD. . Vitamin D deficiency in homebound elderly persons. . JAMA . 1995; ;274: : 1683– 1686 .
    [Google Scholar]
  17. [17]. Lips   P., , Duong   T., , Oleksik   A., , Black   D., , Cummings   S., , Cox   D. . A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial. . J Clin Endocrinol Metab . 2001; ;86: : 1212– 1221 .
    [Google Scholar]
  18. [18]. Sedrani   SH., , Al Arabi   K., , Abanny   A., , Elidrissy   A. . Vitamin D status of Saudis: IV. Seasonal variations. . Saudi Med J . 1992; ;13: : 423– 429 .
    [Google Scholar]
  19. [19]. Sedrani   SH. . Low 25-hydroxyvitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region. . Ann Nutr Metab . 1984; ;28: : 181– 185 .
    [Google Scholar]
  20. [20]. Moore   C., , Murphy   MM., , Keast   DR., , Holick   MF. . Vitamin D intake in the United States. . J Am Diet Assoc . 2004; ;104: : 980– 983 .
    [Google Scholar]
  21. [21]. Tomashek   KM., , Nesby   S., , Scanlon   KS. . Nutritional rickets in Georgia. . Pediatrics . 2001; ;107: : E45– E50 .
    [Google Scholar]
  22. [22]. Looker   AC., , Dawson-Hughes   B., , Calvo   MS., , Gunter   EW., , Sahyoun   NR. . Serum 25-hydroxy vitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III. . Bone . 2002; ;30: : 771– 777 .
    [Google Scholar]
  23. [23]. Kreiter   SR., , Schwartz   RP., , Kirkman   HN., , Charlon   PA., , Calikoglu   AS., , Davenport   ML. . Nutritional rickets in African-American breast-fed infants. . J Pediatr . 2000; ;137: : 153– 157 .
    [Google Scholar]
  24. [24]. Nesby-O'Dell   S., , Scanlon   KS., , Cogswell   ME. . Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994. . Am J Clin Nutr . 2002; ;76: : 187– 192 .
    [Google Scholar]
  25. [25]. Harinarayan   CV. . Prevalence of Vitamin D Insufficiency in Postmenopausal South Indian Women. . Osteoporos Int . 2005; ;16: 4 : 397– 402 , Epub .
    [Google Scholar]
  26. [26]. Holick   MF. . Vitamin D: Importance in the prevention of cancer, Type 1 diabetes, heart disease and osteoporosis. . Am J Clin Nutr . 2004; ;79: : 362– 371 , [Abstract/Free Full Text] .
    [Google Scholar]
  27. [27]. Saul   AW. . Vitamin D: Deficiency, diversity and dosage. . J Orthomolecular Med . 2003; ;18: : 194– 204 .
    [Google Scholar]
  28. [28]. Welch   TR., , Bergstrom   WH., , Tsang   RC. . Vitamin D-deficient rickets: The reemergence of a once conquered disease. . J Pediatr . 2000; ;137: : 143– 145 , [CrossRef][ISI][Medline] .
    [Google Scholar]
  29. [29]. Al Turki   HA., , Sadat-Ali   M., , Al Elq   AH., , Al Mulhim   FA., , Al-Ali   AK. . 25-Hydoxyvitamin D levels among healthy Saudi Arabian women. . Saudi Med J . 2008; ;29: 12 : 1765– 1768 .
    [Google Scholar]
  30. [30]. Gaugris   S., , Heaney   RP., , Boonen   S. . Vitamin D inadequacy among postmenopausal women: A systematic review. . Q J Med . 2005; ;98: : 667– 676 .
    [Google Scholar]
  31. [31]. Gannage-Yared   MH., , Chemali   R., , Yaacoub   N., , Halaby   G. . Hypovitaminosis D in a sunny country: relation to lifestyle and bone markers. . J Bone Miner Res . 2000; ;15: : 1856– 1862 .
    [Google Scholar]
  32. [32]. Mishal   AA. . Effects of different dress styles on Vitamin D levels in healthy young Jordanian women. . Osteoporos Int . 2001; ;12: : 931– 935 .
    [Google Scholar]
  33. [33]. Lips   P. . Vitamin D status and nutrition in Europe and Asia. . J Steroid Biochem Mol Biol . 2007; ;103: : 620– 625 .
    [Google Scholar]
  34. [34]. Clemens   TL., , Adams   JS., , Henderson   SL., , Holick   MF. . Increased skin pigment reduces the capacity of skin to synthesis Vitamin D3. . Lancet . 1982; ;1: : 74– 76 .
    [Google Scholar]
  35. [35]. Holick   MF. . Vitamin D and the skin: photobiology, physiology and therapeutic effect for psoriasis. . In: Heersche   JNM., Kanis   JA. , eds. Bone and mineral research . Amsterdam: : Elsevier;   1990; ; : 313– 366 .
    [Google Scholar]
  36. [36]. Norman   AW. . Sunlight, season, skin pigmentation, vitamin D, and 25-hydroxyvitamin D: integral components of the vitamin D endocrine system. . Am J Clin Nutr . 1998; ;67: : 1108– 1110 .
    [Google Scholar]
  37. [37]. Guzel   R., , Kozanoglu   E., , Guler-Uysal   F., , Soyupak   S., , Sarpel   T. . Vitamin D status and bone mineral density of veiled and unveiled Turkish women. . J Womens Health Gend Based Med . 2001; ;10: : 765– 770 .
    [Google Scholar]
  38. [38]. Grootijans-Geerts   I., , Wielders   JP. . A pilor study of hypovitaminosis D in apparently healthy, veiled, Turkish women: severe vitamin D deficiency in 82%. . Ned Tijdschr Geneeskd . 2002; ;146: : 1100– 1101 .
    [Google Scholar]
  39. [39]. El Sonbaty   MR., , Abdul Ghaffar   NU. . Vitamin D deficiency in veiled Kuwaiti women. . Eur J Clin Nutr . 1996; ;50: : 315– 318 .
    [Google Scholar]
  40. [40]. Islam   MZ., , Akhtaruzzaman   M., , Lamberg-Allardt   C. . Hypovitaminosis D is common in both veiled and nonveiled Bangladeshi women. . Asia Pac J Clin Nutr . 2006; ;15: : 81– 87 .
    [Google Scholar]
  41. [41]. Holick   MF. . The vitamin D epidemic and its health consequences. . J Nutr . 2005; ;135: : 2739S– 2748S .
    [Google Scholar]
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  • Article Type: Research Article
Keyword(s): insufficiency , post-menopausal , Qatar and Vitamin D
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