1887
6 The Anbar 2nd International Medical Conference (AIMCO 2022)
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

This study aims to evaluate the occurrence of Y chromosome azoospermia factor (AZF) microdeletions and assess immune infertility incidence and whether there is a correlation between them.

The sample included 75 infertile men who were referred to private clinics in Ramadi city as a test group and 25 healthy fertile men as a control group. The tests included analysis of seminal fluid and detection of the antibodies against the sperms at both seminal fluid and serum and diagnosed chromosomal deletions via real-time polymerase chain reactions using specific sequence-tagged sites.

The results reveal that 46 (61.33%) patients in the group of infertile men have AZF microdeletions, while no deletions are present in the control group. Out of the 75 infertile men, 5 patients (6.66%) from all the study groups have positive results for anti-sperm antibodies (ASA), while the others have negative results for ASA in both serum and seminal plasma.

The prevalence of AZF microdeletions in our study population is high in Anbar Governorate of Iraq, while we find a low incidence of ASA in this study. All the patients with positive ASA results are without deletions in the Y chromosome’s AZF region. So there is no correlation between AZF microdeletion and ASA generation in infertile men in the current study.

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2022-12-06
2024-06-14
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