oa Effect of Tensile Strain and Shear Stress on the Differentiation of Human Mesenchymal Stem Cells into Endothelial Cells

Stem Cells are undifferentiated cells that have special ability to produce similar cells and differentiate to many functionalized cells. Mechanical stimuli have a determinant effect on morphology and function of body cells, because they are constantly affected by internal and external mechanical loadings. In this research, the importance of mechanical stimuli was assessed on the differentiation of human mesenchymal stem cells (hMSCs) to vascular endothelial cells.