oa Evaluation of Genotoxicity of Medicaments in Sick Patients

The aim of this study was to evaluate the genotoxicity of medication in bucall cells, used in chemotherapy of sick patients with lung cancer. Following chemotherapy treatment, samples were taken five, 10 and 15 days afterwards, with cytobrush, and placed in a ringer solution. Samples were taken from 30 patients suffering from lung cancer; The control group consisted of 30 subjects. A high frequency of micronuclei in exfoliated bucall cells were found after treatment wih medication, but they were not statistically significant. According to this result, we can conclude that chemotherapy induces the micronuclei in bucall cells of patients lung cancer.

Keywords: Genotoxicity / Medicaments / Hospital / Lung

Kemajl Kurteshi, Kasum Letaj, Muharrem Ismaili, Zeqir Shaqiri