1887
Volume 2008, Issue 1
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

Group B Streptococcus infection (GBS) has emerged as a serious disease, infecting 18,000 people in the United States annually including life-threatening illness in about 8,000 newly-born infants. To evaluate the efficiency of the current universal screening strategy for the management of GBS carriers a retrospective analysis was made of the records of 1,620 pregnant women in Qatar, 550 of whom were found to be carriers. These latter were then used as a group to be compared with 450 uninfected pregnant women in terms of nationality, parity, age, treatment, and outcome. Young and nullipara pregnant women had a high incidence of GBS but there was no significant effect on birth mortality and morbidity regardless of whether or not they received treatment with antibiotics. It is suggested that the cost of screening for GBS at the 35 th week of gestation cannot be justified.

Loading

Article metrics loading...

/content/journals/10.5339/qmj.2008.1.8
2008-06-01
2019-11-12
Loading full text...

Full text loading...

References

  1. Cochi SL, Feldman RA. Estimating national incidence of group B streptococcal disease: the effect of adjusting for birth weight. Pedia Infect Dis J. 1983; 2::414415.
    [Google Scholar]
  2. Allardice JG, Baskett TF, Seshia MMK, Bowman N, Malazdrewicz R. Perinatal group B streptococcal colonization and infection. Am J Obstet Gynecol. 1982; 142:617620.
    [Google Scholar]
  3. Gallagher RJ, Fuller CA. Group B streptococcal (GBS) disease complication. J Am Acad Nurse Pract Aug. 1994; 6:8:357361.
    [Google Scholar]
  4. Baker CJ, Edwards MS. Group B streptococcal infections. In: Remington JKlein JO, eds. Infectious diseases of the fetus and newborn infant. 4th ed. Philadelphia: WB Saunders 1995;:9801054.
    [Google Scholar]
  5. Money DM, Dobson S. The prevention of early onset neonatal group B streptococcal disease. JOCG. 2004; 149:826832.
    [Google Scholar]
  6. Wiswell TE, Stoll BJ, Tuggle JM. Management of asymptomatic, term gestation neonates born to mothers treated with intrapartum antibiotics. Pediatr Infect Dis J. 1990; 9::826831.
    [Google Scholar]
  7. Szabo Judit, Molnar Laszlo, Pech Endre, Lintner Ferenc, Bows Vera. Experience in the screening of Streptococcus group B infection during pregnancy: can severe neonatal infection be prevented? Orv Hetil. 2002; 143::14791482.
    [Google Scholar]
  8. Schuchat A, Wenger JD. Epidemiology of group B streptococcal disease: Risk factors, prevention strategies and vaccine development. Epidemiol Rev. 1994; 16::374402.
    [Google Scholar]
  9. Schwartz B, Schuchat A, Oxtoby MJ, Cochi SL, Hightower A, Broome CV. Invasive group B streptococcal disease in adults: A population-based study in metropolitan Atlanta. JAMA. 1991; 266::11121114.
    [Google Scholar]
  10. Miura E, Silveira RC, Procianoy RS. Neonatal sepsis: diagnosis and treatment. J Pediatr (Rio J). 1999 Jul; 75:Suppl 1:S57S62.
    [Google Scholar]
  11. Bloom KC, Ewing CA. Group B Streptococcus (GBS) disease screening and treatment during pregnancy. J Midwifery Womens Health. 2001; 46::1723.
    [Google Scholar]
  12. Pinto NM, Soskolne EI, Pearlman MD, Faix RG. Neonatal early onset group B streptococcal disease in the era of intrapartum chemoprophylaxis. Residual problems. J of Perinatol. 2003; 23::265271.
    [Google Scholar]
  13. Fiore Mitchell T, Pearlman MD, Chapman RL, Bhatt Mehta V, Faix RG. Maternal and transplacental pharmacokinetics of cefazolin. Obstet Gynecol. 2001; 98::10751079.
    [Google Scholar]
  14. Pass MA, Gray BM, Khare S, Dillon HC. Prospective studies of group B streptococcal infections in infants. J Pediatr. 1979; 95::431443.
    [Google Scholar]
  15. Cochi SL, Feldman RA. Estimating national incidence of group B streptococcal disease: the effect of adjusting for birth weight. Pediatr Infect Dis J. 1983; 2::414415.
    [Google Scholar]
  16. Pass MA, Khare S, Dillon HC. Twin pregnancies: Incidence of group B streptococcal colonization and disease. J Pediatr. 1980; 97::635637.
    [Google Scholar]
  17. Siegel JD, McCracken GHJ, Threlkeld N, Milvenan B, Rosenfeld CR. Single dose penicillin prophylaxis against neonatal group B streptococcal infections: A controlled trial in 18,738 newborn infants. N Engl J Med. 1980; 303::769775.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.5339/qmj.2008.1.8
Loading
  • Article Type: Research Article
Keyword(s): Group B Streptococci , Pregnancy and Qatar
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error