1887
Volume 2008, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

The incidence and pattern of breast diseases are well studied in the West and to a lesser extent in neighboring Arab countries but rarely in the State of Qatar. In an attempt to delineate the spectrum of breast diseases of women living in Qatar, records were reviewed and analyzed of breast lesions from 1336 women received by the Department of Laboratory Medicine and Pathology, Hamad Hospital, from 1992 until May 2002. This enabled comparisons with data from other countries in the region and with western countries. Fibroadenoma was the most common lesion encountered (34%), followed by infiltrating ductal carcinoma (22.7%), Fibrocystic changes (15.2%), and Mastitis and Abscess (8.8%). The mean age for infiltrating ductal carcinoma was 45.4 years compared to 54 years in Western countries. Statistical results were similar to neighboring Arab countries but different from Western countries (i.e. early presentation of carcinoma, and more cases attributed to lactation and pregnancy probably related to the high fertility amongst women in Qatar). The spectrum of breast diseases in Qatar shows little difference compared to neighboring Arab countries but differs from western countries in that, although breast carcinoma is the most common carcinoma affecting women residing in Qatar, its incidence is far less than in the west and it is most prevalent in a younger age group.

Loading

Article metrics loading...

/content/journals/10.5339/qmj.2008.1.10
2008-06-01
2020-09-18
Loading full text...

Full text loading...

References

  1. Qatar National Cancer Society, Annual Report, 2004.
  2. Amr SS, Sa'di ARM, Ilahi F, Sheikh SS. The spectrum of breast disease in Saudi females: a 26-year pathological survey at Dhahran Health Center. Annals of Saudi Medicine. 1995; 15::125132.
    [Google Scholar]
  3. Amr SS. Breast disease in Jordanian females: a study of 1000 cases. Europ J. Surg Oncol. 1985; 11::257262.
    [Google Scholar]
  4. Anim JT, Sohaibani MO, Grant CS, Tamimi D. Breast cancer as seen at King Fahd Hospital, Al-Khobar 1983–1986. J R Coll Surg Edin. 1989; 34::201204.
    [Google Scholar]
  5. Sengupta H, Al Sulaimani SH, Alam MK, Girgis A. Spectrum of breast disease seen in a hospital breast clinic in Riyadh. J R Coll Surg Edin. 1987; 32::145147.
    [Google Scholar]
  6. Abdin FH, Jawfik HN, Khalil AM. Experience with the pathology of breast lesions. Kasr El Aini J Surg. 1973; 13::95114.
    [Google Scholar]
  7. Dajani YE, Al Jitawi SA. A study of405 breast tumors in Jordanians using the revised WHO classification. Trop Geogr Med. 1987; 39::182186.
    [Google Scholar]
  8. Chiedozi LC, El Hag 1A, Kollur SM. Breast diseases in the Northern region of Saudi Arabia. Saudi Med J. 2003; 24:6:623627.
    [Google Scholar]
  9. Jamal AA. Pattern of breast diseases in a teaching hospital in Jeddah, Saudi Arabia. Saudi Med J. 2001; 22::110113.
    [Google Scholar]
  10. Altaf FJ. Pattern of breast disease, King Khalid National Guard Hospital experience. Annals of Saudi Medicine. 2001; 21::34.
    [Google Scholar]
  11. Mansoor I. Profile of female breast lesions in Saudi Arabia. J Pak Med Assoc. 2001 Jul; 51:7:243247.
    [Google Scholar]
  12. Cheatle GL. Hyperplasia of epithelial and connective tissues in the breasts: its relation to fibroadenoma and other pathologic conditions. Br J Surg. 1923; 10::436455.
    [Google Scholar]
  13. Oliver RL, Major RC. Cyclomastopathy: A physio-pathological conception of some benign breast tumors,with analysis of four hundred cases. Am J Cancer. 1934; 21::1185.
    [Google Scholar]
  14. Al Idrissi HY. Pattern of breast cancer in Saudi females in Eastern Province of Saudi Arabia. Indian J Med Sci. 1991; 45::8587.
    [Google Scholar]
  15. Mokhtar AM, Bedeiwy A. Clinicopathological study of carcinoma of breast at King Abdulaziz University Hospital. King Abdulaziz Med J. 1982; 2::2535.
    [Google Scholar]
  16. Ibrahim EM. Pattern and prognosis of breast cancer: Data from Eastern Province of Saudi Arabia. Saudi Med J. 1991; 12::227231.
    [Google Scholar]
  17. Hidayatallah A. Carcinoma of the breast in Sudan. Epidemiological survey. Sudan Med J. 1969; 7::4349.
    [Google Scholar]
  18. Tarawneh MS. Breast cancer in Jordan. A pathological review. J Kuwait Med Assoc. 1980; 14::7986.
    [Google Scholar]
  19. Barak F, Zippin C, Awad EJ, Houser AR, Horn Y. Breast cancer at Medical Centers in Israel, West Bank and United States. Oncol. 1988; 45::354359.
    [Google Scholar]
  20. Ibrahim EM, Al Mulhim FA, Al Amri A, Al Muhanna FA, Ezzat AA, Stuart RK, Ajarim D. Breast cancer in the eastern province of Saudi Arabia. Med Oncol. 1998 Dec; 15:4:241247.
    [Google Scholar]
  21. Tavassoli FA. Pathology of the breast, Second Edition 1999, McGraw-Hill, page 403.
  22. Parker SL, Davis KJ, Wingo PA. Cancer statistics by race and ethnicity. CA Cancer J Clin. 1998; 48::3148.
    [Google Scholar]
  23. Hoogstraten B, Gad El Mawla N, Hamsa MR, Abdelaziz I, Omar Y. Breast cancer in Arabic women. Oncology. 1982; 39:3:134139.
    [Google Scholar]
  24. El Harith HA, Abdel Hadi MS, Steinmann D, Dork T. BRCA-1 and BRCA-2 mutations in breast cancer patients from Saudi Arabia. Saudi Med J. 2002 June; 23:6:700704.
    [Google Scholar]
  25. Malone KE, Dalling JR, Neal C, Suter NM, O'Brien C, Cushing-Haugen K, Jonasdottir TJ, Thompson JD, Ostrander EA. Frequency of BRCA-1/BRCA-2 mutations in a population-based sample of young breast carcinoma cases. Cancer. 2000 Mar 15; 88:6:13931402.
    [Google Scholar]
  26. Al Kuraya K, Schraml P, Sheikh S, Amr S, Torhorst J, Tapia C, Novotny H. Predominance of high-grade pathway in breast cancer development of Middle East women. Modern Pathology. 2005; 18::891897.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.5339/qmj.2008.1.10
Loading
  • Article Type: Research Article
Keyword(s): breast cancer , breast diseases , Epidemiology , Qatar and young age
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error