1887
Volume 2006, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Various hematological abnormalities commonly occur in active tuberculosis (TB) but thrombocytopenia is exceed-ingly rare and immune thrombocytopenic purpura (ITP) is reported in only a few cases. A 28-year-old male pre-sented with thrombocytopenia-induced epistaxis and gen-eralized purpura that did not respond to intravenous im-munoglobulin but did resolve after antituberculous treat-ment The characteristics of this rarely documented asso-ciation are reviewed.

Loading

Article metrics loading...

/content/journals/10.5339/qmj.2006.1.20
2006-06-01
2024-03-28
Loading full text...

Full text loading...

References

  1. Glasser RM, Walker RI, Herion JC. The significance of hema-tologic abnormalities in patients with tuberculosis. Arch Intern Med. 1970; 125:4:691695.
    [Google Scholar]
  2. Maartens G, Willcox PA, Benatar SR. Miliary tuberculosis: Rapid diagnosis, haematologic abnormalities and outcome in 1 09 treated adults. Am L Med. 1990; 89::291296.
    [Google Scholar]
  3. Hunt BJ, Anderws V, Pettingale KW. The significance of pancytopenia in military tuberculosis. Postgrad Med J. 1987; 63::801804.
    [Google Scholar]
  4. George JN, Raskob GE. Idiopathic thrombocytopenic purpura. Diagnosis and managwement. Am J Med Sci. 1998; 316:2:8793.
    [Google Scholar]
  5. Jurak SS, Aster R, Sawaf H. Immune thrombocytopenia asso-ciated with tuberculosis. Clin pediatr. 1983; 22:4:318319.
    [Google Scholar]
  6. George JN, Woolf SH, Raskob JE, Wasser JS, Aledort LM, Ballem PJ, et al., idiopathic thrombocytopenic purpura: A practice guidlinesby explicit methods for the American Society of Hematology. Blood. 1996; 88:1:340.
    [Google Scholar]
  7. Kalinowiski SZ, Walker JM. Thrombocytopenic purpura in tuberculosis. Br J Tuberc. 1956; 50::239243.
    [Google Scholar]
  8. Almajed SA, Almomen AK, Alkassimi FA, Alzeer A, Kambal AM, Baaqil H. Tuberculosis presented as immune thrombo-cytopenic purpura. Acta Haematol. 1995; 94::135138.
    [Google Scholar]
  9. Spedini P. Tuberculosis presenting as immune thrombocyto-penic purpura. Haematologica. 2002; 87:02:09.
    [Google Scholar]
  10. Ghobrail MW, Albornoz MA. Immune thrombocytopenia: A rare presenting manifestation of tuberculosis. Am J Hem. 2001; 67::139143.
    [Google Scholar]
  11. Perez de Liano LA, Soulan del Cerro JL, Garcia Pais MJ. Immune thrombocytopenic purpura as presenting form of military tuberculosis. Arch Bronch-Pneumol. 1998; 8::411412.
    [Google Scholar]
  12. Talbot S, Dowling A, Dowling JP, Fuller A, Schwartz M. Mediastinal nodal tuberculosis presenting as immune thrombocytopenia. Aust NZJ Med. 1998; 28:4:465466.
    [Google Scholar]
  13. Hernandez-Maraver D, Peleaz J, Pinilla J, Navarro FH. Immune thrombocytopenic purpura due to disseminated tuberculosis. Acta Haematol. 1996; 96:4:266.
    [Google Scholar]
  14. Yasuda Y, Matsubara Y, Watanabe S, Hatakenaka R, Funatsu T. A case of intractable pulmonary tuberculosiscomplicated by idiopathic thrombocytopenic purpura. Nippon Kyobu Geka Gakkai Zasshi. 1994; 42:12:23012305.
    [Google Scholar]
  15. Pavithran K, Vijayalekshmi N. Thrombocytopenic purpura with tuberculous adenitis. Indian J Med Sci. 1993; 47:10:239240.
    [Google Scholar]
  16. Boots RJ, Roberts AW, McEvoy D. Immune thrombocytopenia complicating pulmonary tuberculosis. Case report and inves-tigation of mechanism. Thorax. 1992; 47:5:396397.
    [Google Scholar]
  17. Singh SP, Misra GC, Prusty PK, Das RK. Tubercolar lympha-denitis with purpura. J Indian Me Assoc. 1986; 84:8:247249.
    [Google Scholar]
  18. Jurak SS, Aster R, Sawaf H. immune thrombocytopenia asso-ciated with tuberculosis. Clin Pediat. 1979; 22:4:318319.
    [Google Scholar]
  19. Chia YC, Machin SI. Tuberculosis and severe thrombocyto-penia. Br J Clin Pract. 1979; 33:2:5556.
    [Google Scholar]
  20. Cockcroft DW, Donevan RE, Copland GM, Ibott JW. Miliary tuberculosis presenting with hyponitraemia and thrombocyto-penia. Clin Med Assoc J. 1976; 115:9:871873.
    [Google Scholar]
  21. Levy M, Coopper BA. Thrombocytopenic purpura associated with tuberculous lymphadenitis. Cand Med Assoc J. 1964; 90::373374.
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.5339/qmj.2006.1.20
Loading
  • Article Type: Case Report
Keyword(s): idiopathic thrombocytopenia purpuraimmune thrombocytopenia and Tuberculosis
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error