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Volume 2005, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Background: Primary Sjogren's Syndrom(SS) is an autoimmune disease with diverse clinical presentation. This study was conducted to describe the clinical and immunological picture of SS in patients seen in the main hospital in Qatar.

Methods: We reviewed all the medical records of patients seen at Hamad medical corporation between 1997 and 2002 who met the classification criteria for primary SS. Eighteen patient met these criteria.

Results: Female to male ratio were 9:1. The average age at the time of diagnosis was 40.6 (range from 24-61) with a period of 2.3 years before the diagnosis was established. Dry eyes and/or dry mouth were the presenting symptoms in 66%. Parotid swelling alone or with other symptoms were the presenting symptoms in 17%..Renal tubular acidosis were seen in 17% and fatigue in 44%. Shirmer test was positive in 85% and lip biopsy in 80% of patients in whom the tests were done.Anti-SS-A/Ro were positive in 71% and Anti-SS-B/La were positive in 50%.

Conclusion: Our results are almost similar to other studies in the west.

© 2005 Hammoudeh, Mahdi, licensee Bloomsbury Qatar Foundation Journals.
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/content/journals/10.5339/qmj.2005.1.16
2005-06-01
2024-04-19
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References

  1. Talal N. Sjogren's syndrome. Clinical Aspects of Autoimmunity. 1989; 3:4:6–18.
     [Google Scholar]
  2. Moutsopoulos HM, Bombardieri S. Sjogren's Syndrome. Rheumatology in Europe. 1995; 24:2:46–47.
     [Google Scholar]
  3. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, et al., Classification criteria for Sjogren's syndrome: A revised version of the European proposed by the American-European Consensus Group. Ann Rheum Dis. 2002; 61::554–558.
     [Google Scholar]
  4. Pavlidis NA, Karsh J, Moutsopoulos HM. The clinical picture of primary Sjogren's syndrome: A retrospective study. J Rheumatol. 1982; 9::685–690.
     [Google Scholar]
  5. Oxholm P, Asmussen K. Classification of disease manifestation in primary Sjogren's Syndrom: Present Status and a new proposal. Clinical Rheumatology. 1995; 14::3–7.
     [Google Scholar]
  6. Venables PJW. Sjogren's Syndrome. In: Warrel DACox TMFirth JDBenz EJ Jr, eds. Oxford Textbook of Medicine. fourth edition. Oxford: Oxford University press 2003;:110–113.
     [Google Scholar]
  7. Kraus A, Alarcon-Segovia Donato. Primary Juvenile Sjogren's Syndrome. J Rheumatol. 1988; 15::803–806.
     [Google Scholar]
  8. Jonsson R, Haga HJ, Gordon TP. Sjogren's Syndrome. In: Koopman WJ, ed. Arthritis and allied Conditions. 14th edition. Philadelphia: Lippincot Williams & Wilkins 2001;:1736–1754.
     [Google Scholar]
  9. Tzioufas AG, Moutsopoulos HM. Sjogren's syndrome. In: Klippel JHDieppe PA, eds. Rheumatology. 2nd edition. London: Mosby 1998;:7–32.
     [Google Scholar]
  10. Smeenk RJT. Ro/SS-A and La/SS-B: Autoantigens in Sjogren's Syndrome. Clinical Rheumatology. 1995; 14:suppl. l:11–16.
     [Google Scholar]
  11. Uppal SS, Al-Mutairi M, Mlaviya A. Clinical and immunological profile of primary Sjogren's syndrome in Kuwait: First report from the Middle East. APLAR journal of Rheumatology. 2003; 6:1:16–20.
     [Google Scholar]
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  • Article Type: Case Report

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