1887
Volume 2025, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Fecaloma is a mass of hardened feces impacted in the rectum and sigmoid. When the colonic mucosal wall and vasculature are compressed, stercoral colitis, a rare type of inflammatory colitis, may occur. Despite being connected to psychiatric patients and antipsychotic medications in the literature, fecaloma remains a significant, yet often overlooked, cause of morbidity and mortality in this population.

A 43-year-old patient with schizophrenia being treated with aripiprazole and benztropine lost follow-up and eventually presented to the emergency department with a giant fecaloma and associated stercoral colitis. She was managed with oral and rectal laxatives and supportive therapy. Additionally, aripiprazole was discontinued.

Antipsychotics have been associated with constipation, fecaloma, and stercoral colitis due to their anticholinergic properties. Benztropine, an antimuscarinic drug commonly used in psychiatric patients to alleviate extrapyramidal symptoms, may further decrease gastrointestinal mobility. Fecaloma and associated stercoral colitis are often diagnosed via imaging, typically a computed tomography scan of the abdomen. Management depends on the severity and generally ranges from conservative treatment to surgical options.

This case describes a schizophrenic patient undergoing treatment with aripiprazole and benztropine who presented with constipation and was diagnosed with a giant fecaloma complicated by stercoral colitis. The patient was managed successfully with aggressive laxatives and discontinuation of aripiprazole. Early recognition and prompt management of fecaloma are essential to mitigate associated complications. In addition, it is important to recognize risk factors for constipation and regularly review home medications, such as antipsychotics, that may cause constipation as a side effect.

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References

  1. Yamasaki M, Funaishi K, Hattori N. Giant fecaloma causing anorexia and dysuria. Clin Gastroenterol Hepatol. 2020; 18:(4):A30.
    [Google الباحث العلمي]
  2. Ghosh G, Shah S, Maltz C. A Case of a giant fecaloma. Clin Gastroenterol Hepatol. 2018; 16:(4):e48.
    [Google الباحث العلمي]
  3. Logre E, Degravi L, Plantefève G, Contou D. A fatal fecaloma. Int J Emerg Med. 2020; 13:(1):46.
    [Google الباحث العلمي]
  4. Usumoto Y, Pollanen MS. Death by fecaloma. Forensic Sci Med Pathol. 2022; 18:(2):201–4.
    [Google الباحث العلمي]
  5. Morano C, Sharman T. Stercoral colitis. In: StatPearls. Treasure Island, FL: StatPearls Publishing. Copyright © 2024, StatPearls Publishing LLC.; 2024.
    [Google الباحث العلمي]
  6. Bae E, Tran J, Shah K. Stercoral colitis in the emergency department: a review of the literature. Int J Emerg Med. 2024; 17:(1):3.
    [Google الباحث العلمي]
  7. Kloub MN, Haddad A, Abushanab M, Al-Maharmeh Q, Hussain M, Al Qazakzeh A, et al. Stercoral colitis-induced ischemia mimicking acute mesenteric ischemia: a case report and literature review. Eur J Case Rep Intern Med. 2024; 11:(3):004328.
    [Google الباحث العلمي]
  8. Elkoundi A, Bensghir M, Haimeur C. Stercoral colitis mimicking appendicitis. Int J Emerg Med. 2017; 10:(1):7.
    [Google الباحث العلمي]
  9. Xu Y, Amdanee N, Zhang X. Antipsychotic-induced constipation: a review of the pathogenesis, clinical diagnosis, and treatment. CNS Drugs. 2021; 35:(12):1265–74.
    [Google الباحث العلمي]
  10. Ahuja A, Patel P, Abdijadid S. Benztropine. In: StatPearls. Treasure Island, FL: StatPearls Publishing. Copyright © 2024, StatPearls Publishing LLC.; 2024.
    [Google الباحث العلمي]
  11. Palmer SE, McLean RM, Ellis PM, Harrison-Woolrych M. Life-threatening clozapine-induced gastrointestinal hypomotility: an analysis of 102 cases. J Clin Psychiatry. 2008; 69:(5):759–68.
    [Google الباحث العلمي]
  12. De Hert M, Hudyana H, Dockx L, Bernagie C, Sweers K, Tack J, et al. Second-generation antipsychotics and constipation: a review of the literature. Eur Psychiatry. 2011; 26:(1):34–44.
    [Google الباحث العلمي]
  13. Sheikh RA, Prindiville T, Yasmeen S. Haloperidol and benztropine interaction presenting as acute intestinal pseudo-obstruction. Am J Gastroenterol. 2001; 96:(3):934–5.
    [Google الباحث العلمي]
  14. Park SJ, Gunn N, Harrison SA. Olanzapine and benztropine as a cause of ischemic colitis in a 27-year-old man. J Clin Gastroenterol. 2012; 46:(6):515–7.
    [Google الباحث العلمي]
  15. Lu Z, Sun Y, Zhang Y, Chen Y, Guo L, Liao Y, et al. Pharmacological treatment strategies for antipsychotic-induced hyperprolactinemia: a systematic review and network meta-analysis. Transl Psychiatry. 2022; 12:(1):267.
    [Google الباحث العلمي]
  16. Keim AA, Campbell RL, Mullan AF, McElhinny ML, Monas J, Finch AS, et al. Stercoral colitis in the emergency department: a retrospective review of presentation, management, and outcomes. Ann Emerg Med. 2023; 82:(1):37–46.
    [Google الباحث العلمي]
  17. Ouaïssi M, Sielezneff I, Benoist S, Pirró N, Cretel E, Chaix JB, et al. Lethal fecaloma. J Am Geriatr Soc. 2007; 55:(6):965–7.
    [Google الباحث العلمي]
  18. Serpell JW, Nicholls RJ. Stercoral perforation of the colon. Br J Surg. 1990; 77:(12):1325–9.
    [Google الباحث العلمي]
  19. Zacharias NA, Lubner MG, Richards ES, Mao L, Pickhardt PJ. Stercoral colitis: CT imaging findings and clinical risk factors. Abdom Radiol (NY). 2023; 48:(10):3050–62.
    [Google الباحث العلمي]
  20. Kim SM, Ryu KH, Kim YS, Lee TH, Im EH, Huh KC, et al. Cecal fecaloma due to intestinal tuberculosis: endoscopic treatment. Clin Endosc. 2012; 45:(2):174–6.
    [Google الباحث العلمي]
  21. Ontanilla Clavijo G, León Montañés R, Sánchez Torrijos Y, López Ruiz T, Bozada García JM. Colonic obstruction secondary to sigmoid fecaloma endoscopically resolved with Coca-Cola®. Rev Esp Enferm Dig. 2017; 109:(4):306–8.
    [Google الباحث العلمي]
  22. Matsuo Y, Yasuda H, Nakano H, Hattori M, Ozawa M, Sato Y, et al. Successful endoscopic fragmentation of large hardened fecaloma using jumbo forceps. World J Gastrointest Endosc. 2017; 9:(2):91–4.
    [Google الباحث العلمي]
  23. Liu FG, Meng DF, Shen X, Meng D, Liu Y, Zhang LY. Coca-Cola consumption vs fragmentation in the management of patients with phytobezoars: a prospective randomized controlled trial. World J Gastrointest Endosc. 2024; 16:(2):83–90.
    [Google الباحث العلمي]
  24. Aziz I, Whitehead WE, Palsson OS, Törnblom H, Simrén M. An approach to the diagnosis and management of Rome IV functional disorders of chronic constipation. Expert Rev Gastroenterol Hepatol. 2020; 14:(1):39–46.
    [Google الباحث العلمي]
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  • نوع المستند: Case Report
الموضوعات الرئيسية Antipsychoticsaripiprazolebenztropineconstipationfecaloma and stercoral colitis

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