1887
Volume 2025, Issue 1
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Cancer is a significant global health challenge. One of the biggest health issues that cancer patients face is depression and anxiety. This has a significant impact on their quality of life and treatment outcomes.

The aim of this study was to investigate the frequency of depression and anxiety among cancer patients in Qatar.

This study was a cross-sectional design using the Patient Health Questionnaire-9 (PHQ-9) and Generalized Anxiety Disorder-7 (GAD-7) scales. A total of 500 cancer patients were surveyed from the National Center for Cancer Care and Research in Doha.

The study found that a significant proportion of cancer patients suffered from depression, with an average PHQ-9 score indicating mild levels of severity. Depression was commonly categorized as mild, with a smaller percentage experiencing moderate, moderate-to-severe, or severe depression. Additionally, patients were predominantly anxious, as reflected by an average GAD-7 score, with most patients experiencing mild to moderate symptoms, while a few experienced moderate or severe anxiety. These findings highlight the significant prevalence of both depression and anxiety among cancer patients, pointing to the importance of comprehensive mental health support. Moreover, patients with advanced-stage cancer, those in their 40s and 60s, those undergoing radiotherapy or hormone therapy, and female patients were found to be more susceptible to depression and anxiety.

Treatment of mental health issues is essential to enhancing the effectiveness of cancer treatment. Cancer patients can have a higher quality of life and better adherence to cancer treatments when mental illnesses such as depression and anxiety are identified and treated early. Furthermore, most patients reported having depression and anxiety, according to the study, which showed that these conditions were more common in Qatar than in other countries. Several demographic groups have been linked to higher rates of depression and anxiety, including women, middle-aged adults, people with stage IV cancer, and patients receiving therapies such as radiotherapy and chemotherapy.

© 2025 Alabdulla, Reagu, Alishaq, Al Hammadi, Elkordy, Ghazouani, et al., licensee HBKU Press.
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References

  1. World Health Organization (WHO). Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2018. Int Agency Res Cancer [online]. 2018:13–15. Available from: https://www.iarc.who.int/featured-news/latest-global-cancer-data-cancer-burden-rises-to-18-1-million-new-cases-and-9-6-million-cancer-deaths-in-2018/..
     [Google الباحث العلمي]
  2. Al Ishaq, M., Amie, M.H., Swaidi, A., & Jumaan, S. (2023). Patient Safety Procedure in Mental Health Services A Review Article. NILES journal for Geriatric and Gerontology, 6:(1), 353-392.
     [Google الباحث العلمي]
  3. Global Burden of Disease 2019 Cancer Collaboration; Kocarnik JM, Compton K, Dean FE, Fu W, Gaw BL, Harvey JD, et al. Cancer incidence, mortalit., years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the global burden of disease study 2019. JAMA Oncol. 2022 Mar 1; 8:(3):420–444. doi: 10.1001/jamaoncol.2021.6987.
  4. Die Trill M. Anxiety and sleep disorders in cancer patients. EJC Suppl. 2013 Oct 5; 11:(2):216–224. doi: 10.1016/j.ejcsup.2013.07.009.
     [Google الباحث العلمي]
  5. Breitbart W. Identifying patients at risk for, and treatment of major psychiatric complications of cancer. Support Care Cancer. 1995 Jan; 3:(1):45–60. doi: 10.1007/BF00343921.
     [Google الباحث العلمي]
  6. Pinquart M, Duberstein PR. Depression and cancer mortality: a meta-analysis. Psychol Med. 2010 Nov 40:(11):1797–1810. doi: 10.1017/S0033291709992285.
     [Google الباحث العلمي]
  7. Karstein J, Aass N, Fosså SD, Skovlund E, Dahl AA. Anxiety and depression in cancer patients: relation between the Hospital Anxiety and Depression Scale and the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire. J Psychosom Res. 2000 Jul; 49:(1):27–34. doi: 10.1016/s0022-3999(00)00080-5.
     [Google الباحث العلمي]
  8. Habimana S, Biracyaza E, Mpunga T, Nsabimana E, Kayitesi F, Nzamwita P, et al. Prevalence and associated factors of depression and anxiety among patients with cancer seeking treatment at the Butaro Cancer Center of Excellence in Rwanda. Front Public Health. 2023 February 16;11:972360. doi: 10.3389/fpubh.2023.972360.
     [Google الباحث العلمي]
  9. Niedzwiedz CL, Knifton L, Robb KA, Katikireddi SV, Smith DJ. Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority. BMC Cancer. 2019 Oct 11; 19:(1):943. doi: 10.1186/s12885-019-6181-4.
     [Google الباحث العلمي]
  10. Wang Y, Duan Z, Ma Z, Mao Y, Li X, Wilson A, et al. Epidemiology of mental health problems among patients with cancer during COVID-19 pandemic. Transl Psychiatry. Jul 31; 10:(1):263. doi: 10.1038/s41398-020-00950-y.
     [Google الباحث العلمي]
  11. Khalil A, Faheem M, Fahim A, Innocent H, Mansoor Z, Rizvi S, et al. Prevalence of Depression and anxiety amongst cancer patients in a hospital setting: A cross-sectional study. Psychiatry J. 2016 Sep 26;2016:3964806. doi: 10.1155/2016/3964806.
     [Google الباحث العلمي]
  12. Clinton-McHarg T, Carey M, Sanson-Fisher R, Tzelepis F, Bryant J, Williamson A. Anxiety and depression among haematological cancer patients attending treatment centres: Prevalence and predictors. J Affec Disord. 2014 Aug; 165:176–181. doi: 10.1016/j.jad.2014.04.072.
     [Google الباحث العلمي]
  13. Tsaras K, Papathanasiou IV, Mitsi D, Veneti A, Kelesi M, Zyga S, et al. Assessment of Depression and anxiety in breast cancer patients: Prevalence and associated factors. Asian Pac J Cancer Prev. 2018 Jun 25; 19:(6):1661–1669. doi: 10.22034/APJCP.2018.19.6.1661.
     [Google الباحث العلمي]
  14. Abuelgasim KA, Ahmed GY, Alqahtani JA, Alayed AM, Alaskar AS, Malik MA. Depression and anxiety in patients with hematological malignancies, prevalence, and associated factors. Saudi Med J. 2016 Aug; 37: (8):877–881. doi: 10.15537/smj.2016.8.14597.
     [Google الباحث العلمي]
  15. Uwayezu MG, Gishoma D, Sego R, Mukeshimana M, Collins A. Anxiety and depression among cancer patients: Prevalence and associated factors at a Rwandan Referral Hospital. Rwanda J Med Health Sci. 2019 May; 2:(2):118. doi: 10.4314/rjmhs.v2i2.7.
     [Google الباحث العلمي]
  16. Wondimagegnehu A, Abebe W, Abraha A, Teferra S. Depression and social support among breast cancer patients in Addis Ababa, Ethiopia. BMC Cancer. 2019 Aug 27; 19:(1):836. doi: 10.1186/s12885019-6007-4.
     [Google الباحث العلمي]
  17. Berihun F, Haile S, Abawa M, Mulatie M, Shimeka A. Prevalence and correlates of anxiety and depression among cancer patients in the University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia. Arch Depress Anxiety. 2017 Sep; 3:(2):042–048. doi: 10.17352/2455-5460.000022.
     [Google الباحث العلمي]
  18. Vodermaier A, Linden W, MacKenzie R, Greig D, Marshall C. Disease stage predicts post-diagnosis anxiety and depression only in some types of cancer. Br J Cancer. 2011 Dec 6; 105:(12):1814–1817. doi: 10.1038/bjc.2011.503.
     [Google الباحث العلمي]
  19. Wang Y, Lin Y, Chen J, Wang C, Hu R, Wu Y. Effects of Internet-based psycho-educational interventions on mental health and quality of life among cancer patients: a systematic review and meta-analysis. Support Care Cancer. 2020 Jun; 28:(6):2541–2552. doi: 10.1007/s00520-020-05383-3.
     [Google الباحث العلمي]
  20. Lwanga SK, Lemeshow S, . World Health Organization. Sample size determination in health studies: a practical manual / S.K. Lwanga and S. Lemeshow [online]. World Health Organization; 1991. Available from: https://iris.who.int/handle/10665/40062.
     [Google الباحث العلمي]
  21. Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep; 16:(9):606–613. doi: 10.1046/j.1525-1497.2001.016009606.x.
     [Google الباحث العلمي]
  22. Sun Y, Fu Z, Bo Q, Mao Z, Ma X, Wang C. The reliability and validity of PHQ-9 in patients with major depressive disorder in psychiatric hospital. BMC Psychiatry. 2020 Sep 29; 20:(1):474. doi: 10.1186/s12888-020-02885-6.
     [Google الباحث العلمي]
  23. Mossman SA, Luft MJ, Schroeder HK, Varney ST, Fleck DE, Barzman DH, et al. The generalized anxiety disorder 7-item scale in adolescents with generalized anxiety disorder: Signal detection and validation. Ann Clin Psychiatry. 2017 Nov; 29:(4):227–234A.
     [Google الباحث العلمي]
  24. Krebber AMH, Buffart LM, Kleijn G, Riepma IC, de Bree R, Leemans CR, et al. Prevalence of depression in cancer patients: a meta-analysis of diagnostic interviews and self-report instruments. Psychooncology. 2014 Feb; 23:(2):121–130. doi: 10.1002/pon.3409.
     [Google الباحث العلمي]
  25. Evans-Lacko S, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Benjet C, Bruffaerts R, et al. Socio-economic variations in the mental health treatment gap for people with anxiety, mood, and substance use disorders: results from the WHO World Mental Health (WMH) surveys. Psychol Med. 2018 Jul; 48:(9):1560–1571. doi: 10.1017/S0033291717003336.
     [Google الباحث العلمي]
  26. Annunziata MA, Muzzatti B, Bidoli E, Flaiban C, Bomben F, Piccinin M, et al. Hospital Anxiety and Depression Scale (HADS) accuracy in cancer patients. Support Care Cancer. 2020 Aug; 28::3921–3926. doi: 10.1007/s00520-019-05244-8.
     [Google الباحث العلمي]
  27. Chien CH, Chuang CK, Liu KL, Wu CT, Pang ST, Tsay PL, et al. Effects of individual and partner factors on anxiety and depression in Taiwanese prostate cancer patients: A longitudinal study. Eur J Cancer Care. 2018 Mar; 27:(2):e12753. doi: 10.1111/ecc.12753.
     [Google الباحث العلمي]
  28. Geue K, Göbel P, Leuteritz K, Nowe E, Sender A, Stöbel-Richter Y, et al. Anxiety and depression in young adult German cancer patients: Time course and associated factors. Psycho-Oncology. 2019 Oct; 28:(10):2083–2090. doi: 10.1002/pon.5197.
     [Google الباحث العلمي]
  29. Walker J, Holm Hansen C, Martin P, Sawhney A, Thekkumpurath P, Beale C, et al. Prevalence of depression in adults with cancer: a systematic review. Ann Oncol. 2013 Apr; 24:(4):895–900. doi: 10.1093/annonc/mds575.
     [Google الباحث العلمي]
  30. Walker J, Hansen CH, Martin P, Symeonides S, Ramessur R, Murray G, et al. Prevalence, associations, and adequacy of treatment of major depression in patients with cancer: a cross-sectional analysis of routinely collected clinical data. Lancet Psychiatry. 2014 Oct; 1:(5):343–350. doi: 10.1016/S2215-0366(14)70313-X.
     [Google الباحث العلمي]
  31. Tsoutsi V, Papadakaki M, Yannis G, Pavlou D, Basta M, Chliaoutakis J, et al. Driving behaviour in depression based on subjective evaluation and data from a driving simulator. Int J Environ Res Public Health. 2023 Apr 21; 20:(8):5609. doi: 10.3390/ijerph20085609.
     [Google الباحث العلمي]
  32. Ayalew M, Deribe B, Duko B, Geleta D, Bogale N, Gemechu K, et al. Prevalence of depression and anxiety symptoms and their determinant factors among patients with cancer in southern Ethiopia: a cross-sectional study. BMJ Open. 2022 Jan 21; 12:(1):e051317. doi: 10.1136/bmjopen-2021-051317.
     [Google الباحث العلمي]
  33. Saeedi Z, Bahrainian SA, Ahmadi SM. Effectiveness of positive psychology group therapy in reducing depression, stress and death anxiety in patients with cancer undergoing chemotherapy. J Fundam Ment Health. 2016 Nov; 18: (Special Issue):583–587. doi: 10.22038/jfmh.2016.8420.
     [Google الباحث العلمي]
  34. Venkataramu VN, Ghotra HK, Chaturvedi SK. Management of psychiatric disorders in patients with cancer. Indian J Psychiatry. 2022 Mar 23; 64:(Suppl 2):S458–S472. doi: 10.4103/indianjpsychiatry.indianjpsychiatry_15_22.
     [Google الباحث العلمي]
  35. Wen S, Xiao H, Yang Y. The risk factors for depression in cancer patients undergoing chemotherapy: a systematic review. Support Care Cancer. 2019 Jan; 27:(1):57–67. doi: 10.1007/s00520-018-4466-9.
     [Google الباحث العلمي]
  36. Farokhzadian AA, Andalib L, Yousefvand M. The effectiveness of acceptance and commitment therapy on reducing depression in Cancer Patients. Clin Psychol Pers. 2020; 17:(1):45–52. doi: 10.22070/cpap.2020.2882.
     [Google الباحث العلمي]
  37. Goerling U, Hinz A, Koch-Gromus U, Hufeld JM, Esser P, Mehnert-Theuerkauf A. Prevalence and severity of anxiety in cancer patients: results from a multi-center cohort study in Germany. J Cancer Res Clin Oncol. 2023 Aug; 149:(9):6371–6379. doi: 10.1007/s00432-023-04600-w.
     [Google الباحث العلمي]
  38. Darvishi N, Ghasemi H, Rahbaralam Z, Shahrjerdi P, Akbari H, Mohammadi M. The prevalence of depression and anxiety in patients with cancer in Iran: a systematic review and meta-analysis. Support Care Cancer. 2022 Dec; 30:(12):10273–10284. doi: 10.1007/s00520-022-07371-1.
     [Google الباحث العلمي]
  39. Yang YL, Liu L, Wang Y, Wu H, Yang HX, Wang JN, et al. The prevalence of depression and anxiety among Chinese adults with cancer: a systematic review and meta-analysis. BMC Cancer. 2013;13:393. doi: 10.1186/1471-2407-13-393.
     [Google الباحث العلمي]
  40. Radhakrishnan R, Selvaraj H, Chidambaram K, Kv A, James A, Thangavel S. Prevalence of depression and anxiety disorders among cancer patients: An insight from a single institute. Cureus. 2013 Aug 1; 15:(8): e42831. doi: 10.7759/cureus.42831.
     [Google الباحث العلمي]
  41. Bakhiet TE, Ali SM, Bakhiet AM. Prevalence of depression and anxiety among adult patients undergoing chemotherapy in Khartoum, Sudan: A crosssectional study. J Affect Disord Rep. 2021 Dec; 6::10021. doi: 10.1016/j.jadr.2021.100218.
     [Google الباحث العلمي]
  42. Mitchell AJ, Ferguson DW, Gill J, Paul J, Symonds P. Depression and anxiety in long-term cancer survivors compared with spouses and healthy controls: a systematic review and meta-analysis. Lancet Oncol. 2013 Jul; 14:(8):721–732. doi: 10.1016/S1470-2045(13)70244-4.
     [Google الباحث العلمي]
  43. Arvanitou E, Nikoloudi M, Tsoukalas N, Parpa E, Mystakidou K. Factors associated with anxiety and depression in cancer patients: Demographic factors and the role of demoralization and satisfaction with care. Psychooncology. 2023 May; 32:(5):712–720. doi: 10.1002/pon.6115.
     [Google الباحث العلمي]
  44. Truong DV, Bui QTT, Nguyen DT, Moore J. Anxiety among inpatients with cancer: Findings from a hospital-based cross-sectional study in Vietnam. Cancer Control. 2019 Jan-Dec; 26:(1):1073274819864641. doi: 10.1177/1073274819864641.
     [Google الباحث العلمي]
  45. Gontijo Garcia GS, Meira KC, de Souza AH, Guimarães NS. Anxiety and depression disorders in oncological patients under palliative care at a hospital service: a cross-sectional study. BMC Palliat Care. 2023 Aug 15; 22:(1):116. doi: 10.1186/s12904-023-01233-1.
     [Google الباحث العلمي]
  46. Huppert JD. Anxiety disorders and depression comorbidity. In Antony MM, Stein MM, editors. Oxford handbook of anxiety and related disorders. Oxford University Press; 2009.(p. 576–586).
     [Google الباحث العلمي]
  47. Amine, M.H., Sai., M.Y., & Mohamed, N.A. (2021). Factors Affecting Quality of Health Care among Old Adults at Beni-Suef University Hospital. Medico-Legal Update, 21:(2).
     [Google الباحث العلمي]
  48. Ernst M, Beutel ME, Brähler E. Cancer as a risk factor for distress and its interactions with sociodemographic variables in the context of the first wave of the COVID-19 pandemic in Germany. Sci Rep. 2022 Feb 7; 12:(1):2021. doi: 10.1038/s41598-022-06016-x.
     [Google الباحث العلمي]
  49. Shin DW, Park JH, Shim EJ, Parl JH, Choi YJ, Kim SG. The development of a comprehensive needs assessment tool for cancer-caregivers in patient-caregiver dyads. Psychooncology. 2011; 20:(12):1342–1352. doi: 10.1002/pon.1857.
     [Google الباحث العلمي]
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The prevalence of depression and anxiety symptoms and their associated factors among patients with cancer in Qatar: A cross-sectional study
Qatar Medical Journal 2025, 4 (٢٠٢٥); https://doi.org/10.5339/qmj.2025.4
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  • نوع المستند: Research Article
الموضوعات الرئيسية Anxiety, cancer, depression, patients, Qatar and sociodemographic factors

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