1887
Volume 2006, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Acute pharyngitis is one commonest reasons for patients to visit the family physician, 80-90% of cases are caused by viruses particularly adenovirus. The most important bacterial cause is group A streptococcus, which is responsible for about 15% of all cases. Because of the time required to confirm the presence of group A streptococci using throat cultures many commercial antigen detection tests for the rapid identification of group A streptococci directly from throat swabs have been developed utilizing the latex agglutination principle and a result is available within 5 minutes.

Objective: The purpose of this study was to determine the value of using rapid detection procedure (Reveal color strep A test, Murex) for group A streptococci directly from throat swabs.

Material and Method: Data from 200 patients with sore throat attending one of the Public Medical Centers in Amman over 6 month period May 1998-January 1999. Both throat swabs and cultures were taken and throat swabs were subjected using (Reveal color strep A test) for rapid detection. The culture results were interpreted and reported by microbiologist. Data were analyzed by calculating the number of positives and negatives for both swabs and cultures, the specificity, sensitivity and predictive value were determined.

Results: The usefulness of latex test was as follows: Sensitivity 87%, Specificity 98.2%, Predictive value positive 90%, and Predictive value negative 97.6%.

Conclusion: Using tests for the rapid identification may help in establishing a policy for sore throat management in general practice by avoiding unnecessary cultures and antibiotic prescription

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2006-11-01
2024-03-28
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References

  1. Cochi S, Fraser DW, High-tower AW, et al., Diagnosis and treatmen t of streptococcal pharyngitis: Survey of US medical practitioner. In: Shulman ST, ed. Pharyngitis-Management in an Era of Declining Rheumatic Fever. New York, NY: Praeger Publishers 1984;:7394.
    [Google Scholar]
  2.   Attack Rate of WHO Memorandum Recent Advances in Rheumatic Fever Control and Future Prospects. Bull World Health Organization. 1978; 56::887912.
    [Google Scholar]
  3. Durand M, Joseph M, Baker AS. Infections of the upper respiratory tract. ed. Fauci ASBraumwild EIsselbacher KJWilson JDMartin JBKasper DL et al.. Harrison's principles of internal Biblogrebbler medicine. Vol. 1. 14th4 Ed. New York: McGraw-Hill 1998;:179184.
    [Google Scholar]
  4. Radetsky M, Wheeler RC, Roe MH. Comparative Evaluation of Kits for Rapid Diagnosis of Group A Streptococcal Disease. Pedia Infect Dis. 1985; 4::274281.
    [Google Scholar]
  5. Gerber MA, Spadacini LJ, Wright LL, Deutch L. Latex Agglutination Tests for the Rapid Identification of Group A Streptococci Directly from Th roat Swabs. J Pedia. 1984; 105::702705.
    [Google Scholar]
  6. Manual of Clinical Microbiology. In: Lennette EHBalows AHausler WJShadomy HI, eds. Editors. . 4th Ed. Washington DC: American Society for Microbiology 1985;:154175.
    [Google Scholar]
  7. Wannamaker LE, Rev Infect Dis. 1979; 1::967973.
    [Google Scholar]
  8. Brink WR, Rammelkamp CH Jr, Denny FW. Effect of Penicillin and Aureomycin on the Natural Course of Streptococcal Tonsillitis and Pharyngitis. Am J Med. 1951; 10::300.
    [Google Scholar]
  9. Kilbourne ED, Loge JP. The Comparative Effect of Continuous and Intermittent Penicillin Therapy on the Formation of Anti-Streptolysin in Hemolytic Streptococcal Pharyngitis. J Clin Invest. 1948; 27::418.
    [Google Scholar]
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