1887
  1. Home
  2. A-Z Publications
  3. Qatar Medical Journal
  4. Volume 2020, Issue 3
  5. Article
Volume 2020, Issue 3
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Background: Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system. Some environmental factors, such as infection (HPI), are likely to be considered a protective factor in MS. Dietary intake may provide exposure to or have protective effects for MS. The present study aimed to determine the relationship between serum anti-H. pylori IgG antibody (HPIA) level and dietary intake in patients with MS referred to the MS Clinic in Rafsanjan city, Iran.

Methods: The present case-control study was conducted on 97 patients with MS and 95 controls. The two groups had no significant difference in age and gender ( > 0.05). HPIA was checked, and the food frequency questionnaire was completed in both groups to measure nutritional intake. All data were analyzed by the SPSS 20 software using independent t-test, Chi-Square, Mann–Whitney U test, and correlation.

Results: The median serum HPIA level was significantly lower in MS cases than in controls. Furthermore, the median consumption of glutamic acid, arginine, serine, aspartic acid, alanine, proline, and caffeine was significantly lower in MS cases than in controls. A significant positive correlation was found between the levels of linoleic acid, lactose, Ca, molybdenum, galactose, leucine, and valine, and the level of HPIA in controls.

Conclusion: Our study results demonstrated that some dietary nutrients had correlations with MS and HPI. Therefore, professionals from multiple disciplines must find which foods contain these dietary nutrients in future studies.

© 2021 Kiani, Vakilian, Kamiab, Shamsizadeh, licensee HBKU Press.
Loading

Article metrics loading...

/content/journals/10.5339/qmj.2020.45
2021-02-05
2024-04-19
Loading full text...

Full text loading...

/deliver/fulltext/qmj/2020/3/qmj.2020.45.html?itemId=/content/journals/10.5339/qmj.2020.45&mimeType=html&fmt=ahah

References

  1. Milo R, Miller A. Revised diagnostic criteria of multiple sclerosis. Autoimmun Rev. 2014; 13:(4-5):518–24.
     [Google Scholar]
  2. Hemmer B, Kerschensteiner M, Korn T. Role of the innate and adaptive immune responses in the course of multiple sclerosis. Lancet Neurol. 2015; 14:(4):406–19.
     [Google Scholar]
  3. Riccio P, Rossano R. Nutrition facts in multiple sclerosis. ASN Neuro. 2015; 7:(1):1759091414568185.
     [Google Scholar]
  4. Haghikia A, Jörg S, Duscha A, Berg J, Manzel A, Waschbisch A, et al. Dietary fatty acids directly impact central nervous system autoimmunity via the small intestine. Immunity. 2015; 43:(4):817–29.
     [Google Scholar]
  5. Bagur MJ, Murcia MA, Jiménez-MonrealAM, Tur JA, Bibiloni MM, Alonso GL, et al. Influence of diet in multiple sclerosis: a systematic review. Adv Nutr. 2017May15; 8:(3):463–472.
     [Google Scholar]
  6. Komatsu F, Kagawa Y, Kawabata T, Kaneko Y, Kudoh H, Purvee B, et al. Influence of essential trace minerals and micronutrient insufficiencies on harmful metal overload in a Mongolian patient with multiple sclerosis. Curr Aging Sci. 2012; 5:(2):112–25.
     [Google Scholar]
  7. Katz SI. The role of diet in multiple sclerosis: mechanistic connections and current evidence. Curr Nutr Rep. 2018; 7:(3):150–60.
     [Google Scholar]
  8. Shivappa N, Hebert JR, Behrooz M, Rashidkhani B. Dietary Inflammatory index and risk of multiple sclerosis in a case-control study from Iran. Neuroepidemiology. 2016; 47:(1):26–31.
     [Google Scholar]
  9. Bjørnevik K, Chitnis T, Ascherio A, Munger KL. Polyunsaturated fatty acids and the risk of multiple sclerosis. Mult Scler. 2017 23:(14):1830–8.
     [Google Scholar]
  10. Hadgkiss EJ, Jelinek GA, Weiland TJ, Pereira NG, Marck CH, van der Meer DM. The association of diet with quality of life, disability, and relapse rate in an international sample of people with multiple sclerosis. Nutr Neurosci. 2015; 18:(3):125–36.
     [Google Scholar]
  11. Mard SA, Khadem Haghighian H, Sebghatulahi V, Ahmadi B. Dietary factors in relation to Helicobacter pylori infection. Gastroenterol Res Pract. 2014; 2014::826910.
     [Google Scholar]
  12. Eusebi LH, Zagari RM, Bazzoli F. Epidemiology of Helicobacter pylori infection. Helicobacter. 2014; 19::1-5.
     [Google Scholar]
  13. Kasper DL, Fauci AS, Hauser SL, Longo DL, Jameson JL, Loscalzo J. Harrison's principles of internal medicine, (Vol. 1 and Vol. 2): McGraw Hill Professional; 2018.
  14. Morandini M, Firouzi M, Shafizadeh S, Jaferian S, Beiranvand SF, Roostae F, et al. Investigating prevalence of Helicobacter pylori and histological changes in patients with dyspepsia in Khorramabad City during 2013–2015. Med Sci. 2018; 22:(90):111–7.
     [Google Scholar]
  15. Malli C, Pandit L, D'Cunha A, Mustafa S. Environmental factors related to multiple sclerosis in Indian population. PloS One. 2015; 10:(4):e0124064.
     [Google Scholar]
  16. Mohebi N, Mamarabadi M, Moghaddasi M. Evaluation of the relation between Helicobacter pylori and Multiple sclerosis. Razi J Med Sci. 2013; 19:(105):15–20.
     [Google Scholar]
  17. Habek M, Pavičić T, Ruška B, Pavlović I, Gabelić T, Barun B, et al. Establishing the diagnosis of multiple sclerosis in Croatian patients with clinically isolated syndrome: 2010 versus 2017 McDonald criteria. Multiple Sclerosis and Related Disorders. 2018; 25::99–103.
     [Google Scholar]
  18. Mohammadifard N, Sajjadi F, Maghroun M, Alikhasi H, Nilforoushzadeh F, Sarrafzadegan N. Validation of a simplified food frequency questionnaire for the assessment of dietary habits in Iranian adults: Isfahan Healthy Heart Program, Iran. ARYA Atheroscler. 2015; 11:(2):139–46.
     [Google Scholar]
  19. Saloheimo T, González SA, Erkkola M, Milauskas DM, Meisel JD, Champagne CM et al. The reliability and validity of a short food frequency questionnaire among 9–11-year olds: a multinational study on three middle-income and high-income countries. Int J Obes Suppl. 2015; 5::S22–8.
     [Google Scholar]
  20. Salim MA, Eftekharian MM, Taheri M, Yousef Alikhani M. Determining the IgM and IgG antibody titer against CMV and Helicobacter pylori in the serum of multiple sclerosis patients comparing to the control group in Hamadan. Hum Antibodies. 2018; 26:(1):23–8.
     [Google Scholar]
  21. Allameh SF, Nafissi S, Seyedian M, Ayatollahi P, Nooraei M, Zargaran A. The correlation between multiple sclerosis and Helicobacter pylori infection. Int J Enteric Pathog. 2016; 4:(3):e36402.
     [Google Scholar]
  22. Park AM, Omura S, Fujita M, Sato F, Tsunoda I. Helicobacter pylori and gut microbiota in multiple sclerosis versus Alzheimer's disease: 10 pitfalls of microbiome studies. Clin Exp Neuroimmunol. 2017; 8:(3):215–32.
     [Google Scholar]
  23. Pedrini MJF, Seewann A, Bennett KA, Wood AJ, James I, Burton J, et al. Helicobacter pylori infection as a protective factor against multiple sclerosis risk in females. J Neurol Neurosurg Psychiatry. 2015; 86:(6):603–7.
     [Google Scholar]
  24. Yao G, Wang P, Luo X-D, Yu T-M, Harris RA, Zhang X-M. Meta-analysis of association between Helicobacter pylori infection and multiple sclerosis. Neurosci Lett. 2016; 620::1–7.
     [Google Scholar]
  25. Deretzi G, Gavalas E, Boziki M, Tsiptsios D, Polyzos S, Venizelos I, et al. Impact of Helicobacter pylori on multiple sclerosis-related clinically isolated syndrome. Acta Neurol Scand. 2016; 133:(4):268–75.
     [Google Scholar]
  26. Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, et al. Dietary factors and pediatric multiple sclerosis: a case-control study. Mult Scler. 2018; 24:(8):1067–76.
     [Google Scholar]
  27. Ghazavi Y, Bahadoran Z, Nikfarjam M, Moghaddam NB, Mirmiran P, Haidari MR. Comparison of food intake in multiple sclerosis patients and healthy individuals: A hospital-based case-controlled study. Iran J Child Neurol. 2019; 13:(4):143–54.
     [Google Scholar]
  28. Massa J, O'Reilly EJ, Munger KL, Ascherio A. Caffeine and alcohol intakes have no association with risk of multiple sclerosis. Mult Scler. 2013; 19:(1):53–8.
     [Google Scholar]
  29. Hedström A, Mowry EM, Gianfrancesco M, Shao X, Schaefer C, Shen L, et al. High consumption of coffee is associated with decreased multiple sclerosis risk; results from two independent studies. J Neurol Neurosurg Psychiatry. 2016; 87:(5):454–60.
     [Google Scholar]
  30. Cortese M, Chitnis T, Ascherio A, Munger KL. Total intake of different minerals and the risk of multiple sclerosis. Neurol. 2019; 92:(18):e2127–35.
     [Google Scholar]
  31. Bromley L, Horvath PJ, Bennett SE, Weinstock-Guttman B, Ray AD. Nutritional intake correlates with function in persons with mild-to-moderate multiple sclerosis. Int J MS Care. 2019.
     [Google Scholar]
  32. Toro J, Noriega D, Patiño J, Reyes-Mantilla M, Burbano L, Reyes S, et al. Diet during adolescence and association with multiple sclerosis in Colombian patients (P4. 2–061). AAN Enterprises. 2019.
     [Google Scholar]
  33. Mashinchi S, Arefhosseini S, Ebrahimi Mameghani M, Yousefzadeh S, Saberi A. Pattern of diet and supplement consumption among multiple sclerotic patients pre and post diagnosis and their attitudes toward the effects of these parameters on disease progression. J Guilan Univ Med Sci. 2012; 21:(84):1–14.
     [Google Scholar]
  34. Houdaji M, Khosravi E, Rouzbahani R. The relationship between the soil cadmium and multiple sclerosis. J Isfahan Med Sch. 2015; 33:(332).
     [Google Scholar]
  35. Iranmanesh M, Iranmanesh F, Sadeghi H. Serum level of iron, zinc and copper in patients with multiple sclerosis. J Jahrom Univ Med Sci. 2012; 10:(4):1–5.
     [Google Scholar]
  36. Hoseini Z, Behrooz M, Houshyar-rad A, Askari OS, Asadi H, Nematy M. The relationship between fruit and vegetable consumption and multiple sclerosis: a case–control study. JNKUMS. 2016; 7:(3):573–84.
     [Google Scholar]
  37. Shu L, Zheng PF, Zhang XY, Feng YL. Dietary patterns and Helicobacter pylori infection in a group of Chinese adults’ ages between 45 and 59 years old: an observational study. Medicine (Baltimore). 2019; 98:(2):e14113.
     [Google Scholar]
  38. Mard SA, Khadem Haghighian H, Sebghatulahi V, Ahmadi B. Dietary factors in relation to Helicobacter pylori infection. Gastroenterol Res Pract. 2014; 2014::826910.
     [Google Scholar]
  39. Assaad S, Chaaban R, Tannous F, Costanian C. Dietary habits and Helicobacter pylori infection: a cross sectional study at a Lebanese hospital. BMC Gastroenterol. 2018; 18:(1):48.
     [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.5339/qmj.2020.45
Loading
Correlation of Dietary Intake and Helicobacter pylori Infection with Multiple Sclerosis, a Case-Control Study in Rafsanjan, Iran, 2017–18
Qatar Medical Journal 2020, 45 (2021); https://doi.org/10.5339/qmj.2020.45
/content/journals/10.5339/qmj.2020.45
/content/journals/10.5339/qmj.2020.45
Loading

Data & Media loading...

  • Article Type: Research Article
Keyword(s): Helicobacter pylori, Multiple Sclerosis, Dietary Intake, IgG Antibody

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error