Volume 2012, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426


hypothermia (protective hypothermia) has been known to have beneficial effects since ancient times but interest was renewed after two land mark publication a decade ago. The survival as well as quality of life of post cardiac arrest patients depends on neurological outcome. Mild induced hypothermia is recommended for improving the neurological status of these patients. All acute care physician, nurses and emergency medical services personals should be aware of this approach. We report a case of post cardiac arrest that displayed improved neurological status with mild therapeutic hypothermia. A young, female patient experienced perioperative cardiac arrest. Immediate resuscitation lead to return of spontaneous circulation in six minutes. Her post resuscitation Glasgow Coma score (GCS) was five. We induced therapeutic hypothermia—the patient required sedation and a chemical muscle relaxant. After 24 h we began slow rewarming. On day four, her GCS improved to 14, and she was extubated on day 6. She had mild cognitive disorder but was functionally independent. She was transferred to the ward on day 11 and subsequently discharged home. Mild induced therapeutic hypothermia improves neurological status of post cardiac arrest patients; however, it had adverse effect of increased risk for infection, arrhythmia and electrolyte disorders.


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  1. Gilbert M, Busund R, Skagseth A, Åge N, Solbø JP. Resuscitation from accidental hypothermia of 13.7°C with circulatory arrest. Lancet. 2000; 355::375376.
    [Google Scholar]
  2. Seupaul RP, Wilbur LG. Evidence based medicine, does therapeutic hypothermia benefit survivors of cardiac arrest? Ann Emerg Med. 2011; 58::282283.
    [Google Scholar]
  3. Dumas F, Grimaldi D, Zuber B, Fichet J, Charpentier J, Pene F, Vivien B, Varenne O, Carli P, Jouven X, Empana JP, Cariou A. Is hypothermia after cardiac arrest effective in both shockable and nonshockable patients? Circulation. 2011; 123::877886.
    [Google Scholar]
  4. Polderman KH. Application of therapeutic hypothermia in the ICU: opportunities and pitfalls of a promising treatment modality. Part 1: Indications and evidence. Intensive Care Med. 2004; 30::556575.
    [Google Scholar]
  5. Bernard S, Gray TW, Slivester W, Gutteridge G, Smith K. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N EJM. 2002; 346::557563.
    [Google Scholar]
  6. Hinden M, Makie B. Clinically induced hypothermia: why chill our patients? AACN Adv Crit Care. 2006; 17::125132.
    [Google Scholar]
  7. Bernard SA, Buist M, Monteiro O, smith K. Induced hypothermia using large volume, ice cold intravenous fluid in comatose survivors of out-of-hospital cardiac arrest. A preliminary report. Resuscitation. 2003; 56::913.
    [Google Scholar]
  8. Sterz F, Holzer M, Roine R, Zeiner A, Losert H, Eisenburger P, Uray T, Behringer W. Hypothermia after cardiac arrest: a treatment that works. Curr Opinion Crit Care. 2003; 9::205210.
    [Google Scholar]

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Supplementary File 1

  • Article Type: Case Report
Keyword(s): infectionmild induced hypothermiapost cardiac arrest and rewarming
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