1887
Volume 2008, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

In a prospective study at the Surgical Specialty HospitalMedical City Teaching Hospital, Baghdad30 immunocompromised patients with oral candidiasis (thrush) of the tongue were treated with diode laser irradiation, antifungal antibiotics or ordinary light irradiation as a placebo. A fungicidal effect was achieved in those treated by irradiation with 805 nm wavelength semiconductor diode laser using a power of 1W and continuous working mode for 3 minutes for 5 consecutive days, and also in those treated with antimycotics but the laser treatment was shorter (5 days) compared to the antimycotic treatment (10-21 days) and was used successfully in a renal transplant patient without interference with the drug regimen. It is concluded that light from a low power laser may be valuable in the treatment of oral candidiasis, especially in immunocompromised patients where the rate of recurrence is high and development of resistant strains is a possibility.

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2008-12-01
2019-11-19
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References

  1. Richardson MD, David WW. fungal infection diagnosis and management. 3rd ed. USA: Blackwell Publishing 2003;:1126.
  2. Armstrong D, Rubin RH, Young LS. Clinical Approach to Infection in the Compromised Host. New York: Plenum Medical 1981;:195228.
  3. Darouiche RO. Oropharyngeal and esophageal candidiasis in immunocompromised patients: treatment issues. Clinical infectious diseases. 1998; 26::259274.
    [Google Scholar]
  4. Rex JH, Walsh TJ, Sobel JD, et al., Practice guidelines for the treatment of candidiasis. Clinical infectious diseases. 2000; 30::662678.
    [Google Scholar]
  5. Mirela MB, Marinka MS, Vjekoslav J, Alen B. fungicidal effect of diode laser irradiation in patients with denture stomatitis. Laser Surg Med. 2004; 35:4:259262.
    [Google Scholar]
  6. Caria RF, Cristina K, Cleber RM, Vanderlei SB. Microbial reduction in periodontal pockets under exposition of a medium power diode laser: an experimental study in rats. Laser Surg Med. 2004; 35:4:263268.
    [Google Scholar]
  7. Sarkar S, Wilson M. Lethal photosensitization of bacteria in sub gingival plaque from patients with chronic periodontitis. J Periodont Res. 1993; 28::204210.
    [Google Scholar]
  8. Wilson M, Mia N. Sensitization of Candida albicans to killing by low power laser light. J Oral Pathol. Med. 1993; 22::354357.
    [Google Scholar]
  9. Burns T, Wilson M, Pearson GJ. Killing of cariogenie bacteria by light from a gallium aluminium arsenide diode laser. J Dent. 1994; 22::273278.
    [Google Scholar]
  10. Wilson M, Dob son J. Lethal Photosensitization of Oral Anaerobic Bacteria. Clin Infect Dis. 1993; 16:4:S414S415.
    [Google Scholar]
  11. Dob son J, Wilson M. Sensitization of oral bacteria in bio films to killing by light from a law-power laser. Archs Oral Biol. 1992; 37:11:883887.
    [Google Scholar]
  12. Moritz A, Schoop U, Goharkhay K, Schauer P, Doertbudak O, Wernish J, Sperr W. Treatment of periodontal pockets with a diode laser. Lasers Surg Med. 1998; 22:5:302311.
    [Google Scholar]
  13. Moritz A, Gutknecht N, Doertbudak O, Goharkhay K, Schoop U, Schauer P, Sperr W. Bacterial reduction in periodontal pockets through irradiation with a diode laser: A pilot study. J Clin Laser Med Surg. 1997; 15:1:3337.
    [Google Scholar]
  14. Moritz A, Gutknecht N, Schoop U, Goharkhay K, Doertbudak O, Sperr W. Irradiation of infected root canals with a diode laser in vivo: Results of microbiological examinations. Lasers Surg Med. 1997; 21:3:221226.
    [Google Scholar]
  15. Gutknecht N, Van Gogswaardt D, Conrads G, Ape IC, Schubert C, Lampert F. Diode laser radiation and its bactericidal effect in root canal wall dentin. J Clin Laser Med Surg. 2000; 18:2:5760.
    [Google Scholar]
  16. Nussbaum EL, Lilge L, Mazzulli T. Effects of630-, 660-, 810-,and 905-nm laser irradiation delivery radiant exposure of 1-50 J/ cm2 on three species of bacteria in vitro. J Clin Laser Med Surg. 2002; 20:6:325333.
    [Google Scholar]
  17. Nussbaum EL, Lilge L, Mazzlli T. Effects of 810 nm laser irradiation on in vitro growth of bacteria: Comparison of continuous wave and frequency modulated light. Laser Surg Med. 2002; 31:5:343351.
    [Google Scholar]
  18. Gutknecht N, Mortz A, Conards G, Sievert T, Lampert F. Bactericidal effect of the Nd:YAG laser in vitro root canals. J Clin Laser Med Surg. 1996; 14:2:7780.
    [Google Scholar]
  19. Gouw-Soares S, Gutknecht N, Conrads G, Lampart F, Matson E, Eduardo CP. The bactericidal effect of Ho:Yag laser irradiation within contaminated root dentinal samples. J Clin Laser Med Surg. 2000; 18:2:8187.
    [Google Scholar]
  20. Bernard MK, David AP, Curtis DH. Infectious complications of kidney transplantation and their management, Gabriel MD: handbook of kidney transplantation. 3rd ed. USA: Lippincott Williams & Wilkins 2001:p.255.
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  • Article Type: Research Article
Keyword(s): Candida albicans , immunocompromised and low power laser
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