Volume 2007, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426


Lipid-lowering agents such as HMG-CoA reductase inhibitors (also known as statin drugs) are generally well tolerated. But a recognized side effect still can happen, We report a case of 47-year-old Iraqi male patient previously known hypothyroid, was not on replacement therapy, as he did not appear after his thyroid functions was checked came in with severe body pain for 10 months got worse in the last three months, started on lipostat (ten months ago) found to have myopathy as evident by high CPK which improved gradually clinically and biochemical after stopping lipostat.


Article metrics loading...

Loading full text...

Full text loading...


  1. Farmer JA. Learning from the cerivastatin experience (commentary). Lancet. 2001; 358::13835.
    [Google Scholar]
  2. Grundy SM. Can statins cause chronic low-grade myopathy ? Ann Intern Med. 2002; 137::617.
    [Google Scholar]
  3. Grundy SM. HMG CO A reductase inhibitor for treatment of hypercholestrelimia. N Engl J Med. l998 Jul 7; 319:1:2433.
    [Google Scholar]
  4. Hansen KE, Hildebrand JP, Furguson EE. JH Outcomes in 45 patients with statin-associated myopathy. Arch Intern Med. 2005 Dec 12-26; 165:22:26712676.
    [Google Scholar]
  5. Tobert JA. Efficacy and long-term adverse effect pattern of lovastatin. Am J Cardiol. 1988 Nov 11; 62:15:28J34J.
    [Google Scholar]
  6. The Pink Sheet” FDC Reports. 2002; 64 (Vol 23): 5.
  7. Pfeffer MA, Keech A, Sacks FM, Cobbe SM, Tonkin A, Byington RP, Davis BR, Friedman CP, Braunwald E. Safety and tolerability of pravastatin in long-term clinical trials: Prospective Pravastatin Pooling (PPP) Project. Circulation. 2002 May 21; 105:20:23412346.
    [Google Scholar]
  8. Gadbut AP, Caruso AP, Galper JB. Differential sensitivity of C2-C12 striated muscle cells to lovastatin and pravastatin. J Mol Cell Cardiol. 1995 Oct; 27:10:23972402.
    [Google Scholar]
  • Article Type: Case Report
Keyword(s): myopathy and pravastatin
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error