Volume 2006, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426


Mature or peripheral T cell lymphomas (PTCL) are uncommon in most parts of the world and account for only 10-15% of all non-Hodgkin's lymphomas (NHLs). They usually occur in middle-aged to elderly patients, 68% presenting with features characterized by a disseminated disease, with systemic symptoms in nearly half of them (45%), bone marrow (BM) involvement in a quarter (25.8%), and extranodal disease in a third (37%). We report for the first time a patient with a lesion on the glans penis, an unusual site.


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  1. Foss HD, Coupland SE, Stein H. Clinico-pathologic forms of peripheral T-and NK-cell lymphomas. Pathologe. 2000 Mar; 21:2:137146.
    [Google Scholar]
  2. Ascani S, Zinzani PL, Gherlinzoni F, Sabattini E, Briskomatis A, de Vivo A, Piccioli M, Fraternali Orcioni G, Pieri F, Goldoni A, Piccaluga PP, Zallocco D, Burnetii R, Leoncini L, Falini B, Turn S, Pileri SA. Peripheral T-cell lymphomas. Clinico-pathologic study of 168 cases diagnosed according to the R.E.A.L. Classification. Ann Oncol. 1997 Jun; 8:6:583592.
    [Google Scholar]
  3. Lee HJ, Im JG, Goo JM, Kim KW, Choi Bl, Chang KH, Han JK, Han MH. Peripheral T-cell lymphoma: spectrum of imaging findings with clinical and pathologic features. Radiographics. 2003 Jan-Feb; 23:1:726.
    [Google Scholar]
  4. Zucca E, Zinzani PL. Understanding the group of peripheral T-cell lymphomas, unspecified. Curr Hematol Rep. 2005 Jan; 4:1:2330.
    [Google Scholar]
  5. Gilliam AC, Wood GS. Primary cutaneous lymphomas other than mycosis fungoides. Semin Oncol.. Jun 1999; 26:3:290306.
    [Google Scholar]
  6. Yaqoob N, Noorali S, Nasir MI, Pervez S. Non-Hodgkin's lymphomas presenting as cutaneous lesions. J Coll Physicians Surg Pak.. Jan 2003; 13:1:2932.
    [Google Scholar]
  7. Bekkenk MW, Vermeer MH, Jansen PM, van Marion AM, Canninga-van Dijk MR, Kluin PM, Geerts ML, Meijer CJ, Willemze R. Peripheral T-cell lymphomas unspecified presenting in the skin: analysis of prognostic factors in a group of 82 patients. Blood. 2003 Sep; 102:6:22132219.
    [Google Scholar]
  8. Kojima H, Hasegawa Y, Suzukawa K, Mukai HY, Kaneko S, Kobayashi T, Kamoshita M, Shinagawa A, Komeno T, Komatsu T, Mitsuhashi S, Kawachi Y, Yamashita Y, Mori N, Nagasawa T. Clinicopathological features and prognostic actors of Japanese patients with “peripheral T-cell lymphoma, unspecified” diagnosed according to the WHO classification. LeukRes. Dec 2004; 28:12:12871292.
    [Google Scholar]
  9. Fink-Puches R, Zenahlik P, Back B, Smolle J, Kerl H, Cerroni L. Primary cutaneous lymphomas: applicability of current classification schemes (European Organization for Research and Treatment of Cancer. World Health Organization) based on clinic op athologic features observed in a large group of patients. Blood. 2002; 99::800805.
    [Google Scholar]
  10. Lopez-Guillermo A, Cid J, Salar A, Lopez A, Montalban C, Castrillo JM, Gonzalez M, Ribera JM, Brunet S, Garcia-Conde J, Fernandez de Sevilla A, Bosch F, Montserrat E. Peripheral T-cell lymphomas: initial features, natural history, and prognostic factors in a series of 174 patients diagnosed according to the R.E.A.L. Classification. Ann Oncol. 1998 Aug; 9:8:849855.
    [Google Scholar]
  11. Rudiger T, Weisenburger DD, Anderson JR, Armitage JO, Diebold J, MacLennan KA, Nathwani BN, Ullrich F, Muller-Hermelink HK. Non-Hodgkin ’s Lymphoma Classification Project: Peripheral T-cell lymphoma (excluding anaplastic large-cell lymphoma): results from the Non-Hodgkin's Lymphoma Classification Project. Ann Oncol.. Jan 2002; 13:1:140149.
    [Google Scholar]
  12. Gallamini A, Stelitano C, Calvi R, Bellei M, Mattei D, Vitolo U, Morabito F, Martelli M, Brusamolino E, Iannitto E, Zaja F, Cortelazzo S, Rigacci L, Devizzi L, Todeschini G, Santini G, Brugiatelli M, Federico M. Intergruppo Italiano Linfomi: Peripheral T-cell lymphoma unspecified (PTCL-U): A new prognostic model from a retrospective multicentric clinical study. Blood. 2004 Apr; 103:7:24742479.
    [Google Scholar]
  13. Gisselbrecht C. Autologous stem cell transplantation in aggressive non-Hodgkin's lymphoma. Recent Results Cancer Res. 1998; 144::1526.
    [Google Scholar]
  • Article Type: Case Report
Keyword(s): and Non-Hodgkin's lymphomaCutaneous T-Cell lymphoma and penile ulcer
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