1887
Volume 2005, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

Malaria is one of the most widespread infections globally and is undoubtedly responsible for the majority of all cases of transfusion-transmitted disease in the world. Qatar is free from endemic malaria. However; cases are seen with the large expatriate work force imported from malarious areas. These constitute a significant percent of the blood donors’ pool (34%). Over a 27-month period, among 5845 volunteers tested for malaria, 21 were deferred (0.36%) showing positive result when screened by the Giemsastained thick smear technique, with 2 undiagnosed cases that led to transfusion-transmitted malaria. Since then and for the last 21 months, the Falciparum-Spot immunofluorescence (IF) test was implemented in an attempt to ensure accurate screening. Among 6367 donors tested, 274 (4.3%) were deferred. Careful questioning about donor travel history, expansion of deferral policy and the use of a more sensitive screening test have all resulted in increasing layers of safety where no transfusion-transmitted malaria was reported in the last 21 months. These measures were necessary to regain the trust of the public in the safety and stewardship of the blood supply.

Loading

Article metrics loading...

/content/journals/10.5339/qmj.2005.2.9
2005-11-01
2019-08-25
Loading full text...

Full text loading...

References

  1. 1. Malaria Situation in Qatar, 2002. Third Inter-County Meeting of National Malaria Program Managers, Lahore, Pakistan, 12-15 May, 2003 .
  2. 2. Bush   MP., , Kleinman   SH., , Nemo   GJ. . Current and Emerging Infectious risks of blood transfusion. . JAMA . Feb 26   2003; ;289: 8 : 959– 962 .
    [Google Scholar]
  3. 3. Klein   HG. . Will blood transfusion ever be safe enough ?.   JAMA . July 12   2000; ;284: 2 : 239– 240 .
    [Google Scholar]
  4. 4. Centers for Disease Control and Prevention (CDC) . Probable transfusion-transmitted malaria. Houstoun, Texaas, 2003. . MMWR Morb Mortal Wkly Rep . Nov 7   2003; ;52: 44 : 1075– 1076 .
    [Google Scholar]
  5. 5. Keiser   J., , Utzinger   J., , Premji   Z., , Yamagata   Y., , Singer   BH. . Acridine Orange for malaria diagnosis: Its diagnostic performance, its promotion and implementation in Tanzania and the implications for malaria control. . Ann Trop Med Parasitol . Oct   2002; ;96: 7 : 643– 654 .
    [Google Scholar]
  6. 6. Pomper   GJ., , Wu   Y., , Snyder   EL. . Risks of transfusion-transmitted infections. . Curr Op Hematol . Nov   2003; ;10: 6 : 412– 418 .
    [Google Scholar]
  7. 7. Contreras   CE., , Panccce   A., , Macano   N., , Gonzalez   N., , Bianco   N. . Detection of specific antibodies to Plasmodium falciparum in blood bank donors from malaria-endemic and non-endemic areas of Venezuela. . Am J Trop Med Hyg . Jun   1999; ;60: 6 : 948– 953 .
    [Google Scholar]
  8. 8. Snyder   EL., , Dodd   RY. . Reducing the risk of blood transfusion. . Hematology (Am Soc Hematol Educ Program) . 2001; ; : 433– 442 .
    [Google Scholar]
  9. 9. Soullie   B., , Soler   C., , Gerome   P., , Clavier   B., , Multon   L., , Dingreville   M., , Joussemet   M. . Specificity of immunofluorescent methods detecting malarial antibodies: Comparative study in the screening of blood donations. . Transfus Clin Biol . Nov-Dec   2002; ;9: 5-6 : 297– 300 .
    [Google Scholar]
  10. 10. Silvies   O., , Thellier   M., , Rosenheim   M., , Datry   A., , Lavigne   P., , Danis   M., , Mazier   D. . Potential value of Plasmodium Falciparum-associated antigen and antibody detection for screening of blood donors to prevent transfusion-transmitted malaria. . Transfusion . Mar   2002; ;42: 3 : 357– 362 .
    [Google Scholar]
  11. 11. Shehata   N., , Kohli   M., , Detsky   A. . The cost-effectiveness of screening blood donors for malaria by PCR. . Transfusion . Feb   2004; ;44: 2 : 217– 228 .
    [Google Scholar]
  12. 12. Vu   TT., , Tran   VB., , Phan   NT., , Le   TT., , Luong   VH., , O'Brien   E., , Morris   GE. . Screening donor blood for malaria by polymerase chain reaction. . Trans R Soc Trop Med Hyg. . Jan-Feb   1995; ;89: 1 : 44– 47 .
    [Google Scholar]
  13. 13. Sabgaida   TP., , Orlov   VS., , Adak   T. . Phenotypic variability in P. vivax with short- and long-term incubation period. . MedParazitol (Mosk) . Oct-Dec   2000; ;   4 : 18– 22 .
    [Google Scholar]
  14. 14. Davis   TM., , Singh   B., , Sheridan   G. . Parasitic procrastination: Late presenting ovale malaria and Schistosomiasis. . Aug 6   MedJAust . 2001; ;175: 3 : 146– 148 .
    [Google Scholar]
  15. 15. Moody   A. . Rapid diagnostic tests for malaria parasites. . Clin Microbiol Rev Jan; . 2002; ;15: 1 : 66– 78 .
    [Google Scholar]
http://instance.metastore.ingenta.com/content/journals/10.5339/qmj.2005.2.9
Loading
  • Article Type: Research Article
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error