1887
Volume 2005, Issue 1
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

Post-partum choriocarcinoma is a rare complication of pregnancy. We have analyzed a series of six consecutive patients presenting with choriocarcinoma after a fullterm non-molar pregnancy. The incidence was calculated to be 1 in 19,000 births. Five patients were managed at the Hamad Medical Corporation between 1991 and 2001. All presented with persistent primary or secondary post-partum hemorrhage. Treatment with chemotherapy was successful in all cases. Early diagnosis is important because this rare condition is potentially curable with appropriate chemotherapy.

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2005-06-01
2019-12-13
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References

  1. Bagshawe KD, Dent J, Webb J. Hydatidiform mole in England and Wales in 1973–1983. Lancet. 1986; 2::673677.
    [Google Scholar]
  2. Berkowitz RS, Goldstein DP. The management of molar pregnancy and gestational trophoblastic tumors. In: Knapp RCRCBerkowits RS, eds. Gynecologic Oncology. 2nd ed. New York: McGraw-Hill 1993;:328338.
    [Google Scholar]
  3. Sheridan E, Hancock BW, Smith SC, Doreen MS, Neal EE, Pennington GW, Millar DR. Gestational trophoblastic disease: experience of the Sheffield (United Kingdom) supraregional screening and treatment service. Int J Oncol. 1993; 3::149155.
    [Google Scholar]
  4. Bagshawe KD, Dent J, Newlands ES, et al., The role of low dose methotrexate andfolinic acid in gestational trophoblastic tumors. Br J Obstet Gynecol. 1989; 96::795802.
    [Google Scholar]
  5. Bower M, Newlands ES, Holden L, Short D, Brock C, Rustin GJS, Be gent RHJ, Bagshawe KD. (EMA/CO) for high risk gestational trophoblastic tumors: results from a cohort of 272 patients. J Clin Oncol. 1997; 15::236243.
    [Google Scholar]
  6. Surwit EA, Childers JM. High-risk metastatic gestational trophoblastic disease: a new dose-intensive, multiagent chemotherapeutic regimen. J Reprod Med. 1991; 36::4548.
    [Google Scholar]
  7. Seckl MJ, Rustin GJS, newlnads ES, Gwyther SJ, Bomanji J. Pulmonary embolism, pulmonary hypertension, and choriocarcinoma. Lancet. 1991; 338::13131315.
    [Google Scholar]
  8. Hunter V, Raymond E, Christensen C, Olt G, Soper J, Hammond C. Efficacy of the metastatic survey in the staging of gestational trophoblastic disease. Cancer. 1990; 65::16471650.
    [Google Scholar]
  9. Chama CM, Nggada HA, Nuhu A. Cutaneous metastasis of gestational choriocarcinoma. Int J Obstet & Gynecol. 2002; 77::249250.
    [Google Scholar]
  10. Rustin GJS JA, Newlands ES, Foskett M, Fuller S, Short D, Row den P. Presentation and management of choriocarcinoma. After nonmolar pregnancy. Br J Obstet Gynecol. 1995; 102::715719, 22.
    [Google Scholar]
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  • Article Type: Research Article
Keyword(s): chemotherapy , choriocarcinoma and post-partum
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