Volume 2004, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426


The benefits of cholesterol-lowering with statins has been established for patients with high cholesterol levels as well as for patients with prior occlusive coronary heart disease. However; substantial uncertainty has existed about the long-term benefits of these agents in certain groups, including patients with “normal” cholesterol levels pretreatment, women, the elderly, as well as those with prior occlusive non-coronary disease. The Heart Protection Study 1 was designed to resolve these uncertainties and to provide substantially more safety information of statins. We present its significance and practical implications.


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  • Article Type: Review Article
Keyword(s): and tutorialscholesterolCoronary diseaselipid lowering and statins
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