1887
Volume 2002, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

June 2000 heralded the first draft of the human genome and with it a tremendous amount of public attention to this monumental achievement Amidst the excitement regarding the potential impact on clinical medicine and anticipating uthe development of rational strategies for minimizing or preventing disease phenotypes altogether” there has also arisen concern about the ethical use of this new technology as well as a healthy dose of skepticism about its ultimate application to clinical care. Clearly, as technology continues to elucidate new genes and theirfunction, both in normal development and pathology, questions and concerns about practical applications of this information will continue to arise. The goal of this article is to review the impact of the discoveries of Human Genome Project (HGP) on the practice of genetic counselling and clinical care as well as to discuss the potential ethical dilemmas, which may arise.

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/content/journals/10.5339/qmj.2002.1.8
2002-06-01
2024-04-23
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References

  1. Ad Hoc Committee on Genetic Counseling. American Society of Human Genetics. Genetic counseling. Am. J. Hum. Genet. 1975; 27::240242.
    [Google Scholar]
  2. Bartels DM, LeRoy BS, Caplan Al. Prescribing Our Future. New York: Aldine De Gruyter 1993.
    [Google Scholar]
  3. Bieseeker BB, Marteau TM. The future of genetic counselling: an international perspective. Nature Genetics. 1999; 22::133137.
    [Google Scholar]
  4. Collins FS. Shattuck Lecture - Medical and Societal Consequences of the Human Genome Project. NEJM. 1999; 341:1:2837.
    [Google Scholar]
  5. Collins FS, McKusick VA. Implications of the Human Genome Project for Medical Science. JAMA. 2001; 285::540544.
    [Google Scholar]
  6. Geneclinics: http://www.geneclinics.org. A US government supported website maintained by the University of Washington and Seattle Children's Hospital providing a clinical information resource relating genetic testing to the diagnosis, management, and genetic counseling of individuals and families with specific inherited disorders.
  7. Greendale K, Pyeritz RE. Empowering Primary Care Health Professionals in Medical Genetics: How Soon? How Fast? How Far? AJMG. 2001; 106::223232.
    [Google Scholar]
  8. Guttmacher AE, Jenkins J, Uhlmann WR. Genomic Medicine: Who Will Practice It? A Call to Open Arms. AJMG. 2001; 106::216222.
    [Google Scholar]
  9. Holzman NA, Marteau TM. Will Genetics Revolutionize Medicine? NEJM. 2000; 343::141144.
    [Google Scholar]
  10. Mahowald MB, Verp MS, Anderson RR. Genetic Counseling: Clinical and Ethical Challenges. Annu Rev Genet. 1998; 12::547559.
    [Google Scholar]
  11. Nussbaum RL, Mclnes RR, Willard HF. Thompson & Thompson Genetics in Medicine. 6th edition. Phildelphia: W.B. Saunders Co 2001.
    [Google Scholar]
  12. Rice E. The Human Genome Project and gene therapy: a genetic counselor's perspective. J Perinat Neonatal Nurs. 1998 Dec; 12:3:1625.
    [Google Scholar]
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