Volume 1998, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426



Sarcoidosis is an idiopathic granulomatous disease involving one or more multiple organ systems, characterised by the histologic finding of noncaseating epitheloid cell granulomas. This is the first report of familial sarcoidosis in Jordan. We report a mother and her son who Presented with bilateral hilar lymphadenopathy and lung infiltrates.

Sarcoidosis is a rare disease in Jordan. We reported thirty-three cases of sarcoidosis(1). Although the familial tendency is reported in many studies(2), this was not the case in our study. Though the etiology is unknown; both Prevalence of sarcoidosis in different ethnic groups and familial occurrence of the disease strongly suggest the hypothesis of a possible genetic predisposition(3).


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  1. Sharara A.M., Hijazi M., Tarawneh M., Smadi A., Frawan N., Aqla A. Sarcoidosis at King Hussien Medical Center; Initial Report. Journal of the Royal Medical Services (JRMS) 12::1995:4346.
    [Google Scholar]
  2. British Thoracic and Tuberculosis Association. Research Committee Investigation. Familial association in sarcoidosis. BTTA Review. Tubercle (Suppl.) 1972:41.
    [Google Scholar]
  3. James D.G., Williams W.J. Sarcoidosis and other granulomatous disorders. 1985:WB Saunders: Philadelphia.
  4. Lyons D.J., Fielding J.F. What's in a relationship? Sarcoidosis and tuberculosis. Ir Med J 83::21990:7679.
    [Google Scholar]
  5. James D.G., Neville E., Piyasena K.H.G., Waker A.N., Hamlyn A.N. Possible genetic influences in familial sarcoidosis. postgrad Med J 50::1974:664670.
    [Google Scholar]
  6. Pasturenzi L; Martinetti M; Cuccia M; Cipriani A, Semenzato G; Luisetti M. HLA class I, II, and III polymorphism in Italian patients with sarcoidosis. The Pavia-Padova Sarcoidosis Study Group. Chest 104::4 1993:11701175.
    [Google Scholar]
  7. Sharma O.P.. Pulmonary sarcoidosis and corticosteroids. Am Rev Respir Dis 147::6 Pt 1 1993:15981600.
    [Google Scholar]
  • Article Type: Case Report
Keyword(s): Familial and Sarcoidosis
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