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Volume 2023, Issue 4
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

: The coronavirus disease (COVID-19) has devastating pervasiveness throughout the world. Moreover, the presence of comorbidities could worsen the effects of COVID-19. Therefore, our aim was to study the types of comorbidities in COVID-19 patients admitted to a tertiary care hospital and to assess the impact of comorbidities and their outcomes in COVID-19 patients admitted to a tertiary care hospital.

: This was a single-center, observational, ambispective study that included consecutive patients with COVID-19 admitted to a tertiary care hospital in India between April 2020 and March 2022. The data was collected regarding the patients with COVID-19 admitted to the hospital through medical records. Comorbidities were determined based on the patient’s self-report on admission. The primary endpoint of the study was a composite measure that consisted of admission to an intensive care unit (ICU), invasive ventilation, or death.

: A total of 2323 patients were included in the study. The mean age of the patients was 50 years. Hypertension was the most common comorbidity observed in 24.8% of patients, followed by diabetes mellitus in 17.5% of patients. Around 9.5% of patients required invasive ventilation; the ICU admission rate was 14.3%, and the death rate was 10.1%. There was a significant association between the presence of any comorbidity (except cancer) and the death of the patients as well as admission to the ICU ( < 0.001).

: In view of the results, it can be concluded that the comorbidities, namely hypertension, diabetes mellitus, coronary artery disease, COPD/bronchial asthma, chronic kidney disease, and cerebrovascular accidents, except for cancer, were found to have an association with the severity of the illness in terms of ICU admission as well as the death rate in COVID-19 patients.

© 2023 Sengupta, Shukla, Shrihari, Kapoor, Bharat, licensee HBKU Press.
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2023-12-28
2025-01-25
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References

  1. Cascella M, Rajnik M, Aleem A, Dulebohn SC, Di Napoli R. Features, evaluation, and treatment of coronavirus (COVID-19). St. Petersburg, FL: Statpearls [internet]; 2022.
     [Google Scholar]
  2. World Health Organization. COVID-19 weekly epidemiological update, edition 101, 20 July 2022. 2022.
     [Google Scholar]
  3. TIMESOFINDIA. India reports 15,528 Covid-19 cases, 25 deaths in last 24 hours; active cases decline: Times of India; 2022. Available from: http://timesofindia.indiatimes.com/articleshow/92970573.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst
     [Google Scholar]
  4. Ejaz H, Alsrhani A, Zafar A, Javed H, Junaid K, Abdalla AE, et al. COVID-19 and comorbidities: Deleterious impact on infected patients. J Infect Public Health. 2020; 13:(12):1833–9. doi: 10.1016/j.jiph.2020.07.014
     [Google Scholar]
  5. Sanyaolu A, Okorie C, Marinkovic A, Patidar R, Younis K, Desai P, et al. Comorbidity and its impact on patients with COVID-19. SN Compr Clin Med. 2020; 2::1069–76.
     [Google Scholar]
  6. Singh P, Bhaskar Y, Verma P, Rana S, Goel P, Kumar S, et al. Impact of comorbidity on patients with COVID-19 in India: A nationwide analysis. Front Public Health. 2022;10::1027312.
     [Google Scholar]
  7. Singh AK, Misra A. Impact of COVID-19 and comorbidities on health and economics: Focus on developing countries and India. Diabetes Metab Syndr. 2020;14:(6):1625–30.
     [Google Scholar]
  8. Rana R, Ranjan V, Kumar N, Chugh P, Khillan K, Gogia A, et al. Association of underlying comorbidities and progression of COVID-19 infection amongst 2586 patients hospitalised in the National Capital Region of India: A retrospective cohort study. Mol Cell Biochem. 2023; 478:(1):149–60.
     [Google Scholar]
  9. Dosi R, Jain G, Mehta A. Clinical characteristics, comorbidities, and outcome among 365 patients of coronavirus disease 2019 at a tertiary care centre in central India. J Assoc Physicians India. 2020; 68:(9):20–3.
     [Google Scholar]
  10. Kansara N, Nandapurkar AB, Maniyar R, Yadav AK. Prediction of mortality by age and multi-morbidities among confirmed COVID-19 patients: Secondary analysis of surveillance data in Pune, Maharashtra, India. Indian J Public Health. 2021; 65:(1):64–6.
     [Google Scholar]
  11. Deeb A, Khawaja K, Sakrani N, AlAkhras A, Al Mesabi A, Trehan R, et al. Impact of ethnicity and underlying comorbidity on COVID-19 in hospital mortality: An observational study in Abu Dhabi, UAE. Biomed Res Int. 2021;2021.
     [Google Scholar]
  12. Bailly L, Fabre R, Courjon J, Carles M, Dellamonica J, Pradier C. Obesity, diabetes, hypertension and severe outcomes among inpatients with coronavirus disease 2019: A nationwide study. Clin Microbiol Infect. 2022; 28:(1):114–23.
     [Google Scholar]
  13. Fathi M, Vakili K, Sayehmiri F, Mohamadkhani A, Hajiesmaeili M, Rezaei-Tavirani M, et al. The prognostic value of comorbidity for the severity of COVID-19: A systematic review and meta-analysis study. PLoS One. 2021; 16:(2):e0246190.
     [Google Scholar]
  14. Majeed J, Ajmera P, Goyal RK. Delineating clinical characteristics and comorbidities among 206 COVID-19 deceased patients in India: Emerging significance of renin angiotensin system derangement. Diabetes Res Clin Pract. 2020; 167::108349.
     [Google Scholar]
  15. Pranata R, Lim MA, Huang I, Raharjo SB, Lukito AA. Hypertension is associated with increased mortality and severity of disease in COVID-19 pneumonia: A systematic review, meta-analysis and meta-regression. J Renin Angiotensin Aldosterone Syst. 2020; 21:(2).
     [Google Scholar]
  16. Mehta A, Vasudevan S, Parkash A, Sharma A, Vashist T, Krishna V. COVID-19 mortality in cancer patients: A report from a tertiary cancer centre in India. PeerJ. 2021; 9::e10599.
     [Google Scholar]
/content/journals/10.5339/jemtac.2023.38
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An observational study of comorbidities and their outcome in patients with COVID-19 admitted to a tertiary care hospital
Journal of Emergency Medicine, Trauma and Acute Care 2023, 38 (2023); https://doi.org/10.5339/jemtac.2023.38
/content/journals/10.5339/jemtac.2023.38
/content/journals/10.5339/jemtac.2023.38
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Keyword(s): comorbidity, COVID-19, death and intensive care units

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