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- Source: Global Cardiology Science and Practice, Volume 2015, Issue 2, June 2015,
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- 12 March 2015
- 30 April 2015
- 23 June 2015
oa Is there a role for genetic risk assessment in the treatment of dyslipidemia in primary and secondary prevention of coronary heart disease?
Abstract
Genetic variants have been associated with the risk of coronary heart disease (CHD). Mega et al studied the association of a genetic risk score based on 27 genetic variants with incidents of recurrent CHD, adjusting for traditional risk factors using data from a community based study and 4 randomized controlled trials of both primary and secondary prevention with statin therapy. When individuals were divided into low, intermediate and high genetic risk categories, a significant gradient in risk of incident and recurrent CHD was shown.
© 2015 Al Suwaidi, licensee Bloomsbury Qatar Foundation Journals.