Is there a role for genetic risk assessment in the treatment of dyslipidemia in primary and secondary prevention of coronary heart disease?

Jassim Al Suwaidi

doi:10.5339/gcsp.2015.19

ISSN: 2305-7823
EISSN:

oa Is there a role for genetic risk assessment in the treatment of dyslipidemia in primary and secondary prevention of coronary heart disease?
By Jassim Al Suwaidi¹
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Affiliations: ¹ Qatar Cardiovascular Research Center and Adult Cardiology, Heart Hospital, Hamad Medical Corporation, Doha, Qatar
Source: Global Cardiology Science and Practice, Volume 2015, Issue 2, Jun 2015,
DOI: https://doi.org/10.5339/gcsp.2015.19
- Received: 12 March 2015
- Accepted: 30 April 2015
- Published online: 23 June 2015

Abstract

Genetic variants have been associated with the risk of coronary heart disease (CHD). Mega et al studied the association of a genetic risk score based on 27 genetic variants with incidents of recurrent CHD, adjusting for traditional risk factors using data from a community based study and 4 randomized controlled trials of both primary and secondary prevention with statin therapy. When individuals were divided into low, intermediate and high genetic risk categories, a significant gradient in risk of incident and recurrent CHD was shown.

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2015-06-23

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Article Type: Research Article

oa Is there a role for genetic risk assessment in the treatment of dyslipidemia in primary and secondary prevention of coronary heart disease?

Abstract

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