1887
Volume 2007, Issue 1
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

ملخص

Aim: To assess the exocrine pancreatic function among cystic fibrosis patients with cystic fibrosis trans-membrane conductance regulator (CFTR) 11234V mutation. METHODS: Cross-sectional study of 40 cystic fibrosis patients with homozygous CFTR 11234V mutation belonging to a large Arab kindred family and 25 healthy subjects as a control group over a period of 12 mo. Assessment of their exocrine pancreatic function was performed by measuring faecal elastase-1 (FE1) concentration with a commercial ELISA kit using polyclonal antibodies (BioServ Diagnostics) in CF patients compared to healthy subjects. The results were compared with those obtained from a second laboratory using another commercial ELISA (ScheBo; Biotech, Germany) that uses two monoclonal antibodies against different specific epitopes of human pancreatic elastase. RESULTS: All CF patients with CFTR 11234V mutation had normal levels of faecal elastase 1. No significant difference was found between the two methods for the CF groups or between the CF patients with and without pancreatic enzyme replacement.

Loading

جارٍ تحميل قياسات المقالة...

/content/journals/10.5339/qmj.2007.1.26
٢٠٠٧-٠٦-٠١
٢٠٢٤-٠٩-١٩
Loading full text...

Full text loading...

/content/journals/10.5339/qmj.2007.1.26
Loading
  • نوع المستند: Conference Abstract

الأكثر اقتباسًا لهذا الشهر Most Cited RSS feed

هذه الخانة مطلوبة
يُرجى إدخال عنوان بريد إلكتروني صالح
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error