image of Critique of: Blunt splenic trauma: Splenectomy increases early infectious complications: A prospective multicenter study


The study by Demetriades et al., evaluating the effect of different methods of splenic injury management on early infectious complications is both timely and offers new insight into the management of trauma patients. It addresses a common injury with a debatable management approach.

This is a prospective, multicenter study performed over a 22-month period (March 2009–December 2010). All patients with blunt splenic injury admitted to three Level I trauma centers (two centers in USA and one in South Africa) were studied. Patients were categorized according to the final management of their splenic injury into two major groups: splenectomy or splenic preservation. Five outcome measures were evaluated; the development of early intra-abdominal abscess, wound infection, pneumonia, urinary tract infection, and septicemia. All were compared using standard statistical tools.


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  1. Velmahos GC, Jindal A, Chan L, Kritikos E, Vassiliu P, Berne TV, Demetriades D. Prophylactic antibiotics after severe trauma: more is not better. Int Surg. 2001 86:3:176183, Jul–Sep
    [Google Scholar]
  2. Hill GE, Frawley WH, Griffith KE, Forestner JE, Minei JP. Allogeneic blood transfusion increases the risk of postoperative bacterial infection, a meta analysis. J Trauma. 2003 54:5:908914
    [Google Scholar]
  3. Agarwal N, Murphy JG, Cayten CG, Stahl WM. Blood transfusion increases the risk of infection after trauma. Arch Surg. 1993 128:2:171176
    [Google Scholar]
  4. Zhang WB, Li N, Wang PF, Wang GF, Li YS, Li JS. Infections following damage control laparotomy with abdominal packing. Scand J Infect Dis. 2008 40:11–12:867876
    [Google Scholar]
  5. Demetrios D, Thomas S, Elias D, Galinos B, Agathoklis K, John M, Kenji I. Blunt splenic trauma: splenectomy increases early infectious complications: a prospective multicenter study. J Trauma Acute Care Surg. 2012 72:1:229234
    [Google Scholar]
  • Article Type: Commentary Article
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