Volume 2014, Issue 1
  • ISSN: 2305-7823
  • EISSN:


Diabetes mellitus (DM) and obesity are associated with significant morbidity and mortality. Recent large-scale trials of intensive medical management for obesity and diabetes have been disappointing. Observational studies and small-scale trials of bariatric surgery on DM patients have shown promising results. The effects of sleeve gastrectomy and gastric bypass in a larger cohort of patients with DM and obesity was tested in the STAMPEDE trial over a 3-year follow-up.


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  1. Schauer PR, Kashyap Wolski K, Brethauer SA, Kirwan JP, Pothier CE, Thomas S, Abood B, Nissen SE, Bhatt DL. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Eng J Med. 2012; 366::15671576.
    [Google Scholar]
  2. Scahuer PR, Bhatt DL, kirwan JP, Wolski K, Brethauer SA, Naveenthan SD, Aminian A, Pothier CE, Kim ESH, Nissen SE, Kashyap SR, for the STAMPEDE investigators . Bariatric surgery versus intensive medical therapy for diabetes_3-year outcomes. New Eng J Med. 2014;, Mar 31. [Epub ahead of print] PMID: 24679060.
    [Google Scholar]
  3. O'Brien PE, Dixon JB, laurie C, Skinner S, Proiotto J, McNeill J, Strauss B, Marks S, Schachter L, Chapman L, Anderson M. Treatment of mild to moderate obesity with laporoscopic adjustable gastric banding or an intensive medical program: a randomized trial. Ann Intern Med. 2006; 144:9:625633.
    [Google Scholar]
  4. Dixon JB, O'Brien PE, Playfair J, Chapman L, Schachter LM, Skinner S, Proietto J, Bailey M, Anderson M. Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial. JAMA. 2008; 299::316323.
    [Google Scholar]
  5. Mingrone G, Panuuzi S, De Gaetano A, Guidone C, Iaconelli A, Leccesi L, Nanni G, Pomp A, Castagneto M, Ghirlanda G, Rubino F. Bariatric surgery versus conventional medical therapy for type 2 diabetes. N Eng J Med. 2012; 366:15771585.
    [Google Scholar]
  6. Ikramuddin S, Korner J, Lee WJ, Connett JE, Inabnet WB, Billington CJ, Thomas AJ, Leslie DB, Chong K, Jeffery RW, Ahmed L, Vella A, Chuang LM, Bessler M, sarr MG, Swain JM, Laqua P, Jensen MD, Bantle JP. Roux-en-Y gastric bypass vs intensive medical management for the control of type-2 diabetes, hypertension, and hyperlipidemia: the diabetes Surgery Study randomized clinical trial. JAMA. 2013; 309::22402249.
    [Google Scholar]
  7. Liang Z, Wu Q, Chen B, Yu P, Zhao H, Ouyang X. Effect of laporoscopic Roux-en-Y gastric bypass surgery on type-2 diabetes mellitus with hypertension: a randomized controlled trial. Diabetes Res Clin Pract. 2013 May 22; pii: S0168-8227(13)00161-7. doi:10.1016/j.diabres.2013.04.005. [Epub ahead of print].
    [Google Scholar]

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  • Article Type: Research Article
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