1887
Volume 2024, Issue 1
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

ملخص

Introduction: Cerebral venous sinus thrombosis (CVST) is a rare and life-threatening condition that may be encountered during pregnancy and puerperium. The diagnosis of CVST is a challenge because of its varied presentation.

Case Report: A 28-year-old woman presented with headache, projectile vomiting, and generalized tonic–clonic seizures 10 days after delivery by cesarean section. She had an uneventful antenatal period of 38 weeks of gestation. High clinical suspicion and the availability of magnetic resonance venography helped in making a diagnosis of CVST. She was successfully managed with a low-molecular-weight heparin (LMWH) and anti-epileptic therapy with no residual complications.

Discussion: Pregnancy induces several prothrombotic changes in the coagulation system that predispose to CVST. These changes persist for six to eight weeks after birth. Infection and cesarean section are the additional risk factors for CVST during puerperium. The symptoms of CVST depend on the sinuses and veins involved, raised intracranial pressure, and the extent of brain parenchymal injury.

Conclusion: Greater awareness of the disease and the availability of imaging modalities have contributed to the early diagnosis and favorable outcomes in these cases. LMWH is the main stay of treatment in this disease.

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References

  1. Bousser MG, Ferro JM. Cerebral venous thrombosis: an update. Lancet Neurol. 2007; 6:(2):162–70. doi: 10.1016/S1474-4422(07)70029-7
    [Google الباحث العلمي]
  2. Ferro JM. Causes, predictors of death, and antithrombotic treatment in cerebral venous thrombosis. Clin Adv Hematol Oncol. 2006; 4:(10):732–3. PMID: 17099629
    [Google الباحث العلمي]
  3. Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. ISCVT Investigators. Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT). Stroke. 2004 Mar; 35:(3):664–70. doi: 10.1161/01.STR.0000117571.76197.26
    [Google الباحث العلمي]
  4. Hassan MA, Omar AA, Mohamed IA. Postpartum cerebral venous sinus thrombosis: a case report. Vasc Health Risk Manag. 2023 Jan 30; 19:63–7. doi: 10.2147/VHRM.S390098
    [Google الباحث العلمي]
  5. Oh MK, Ryu JH, Jeon WJ, Lee CW, Cho SY. Case report: postpartum cerebral venous thrombosis misdiagnosed as postdural puncture headache. BMC Anesthesiol. 2020 Apr 7; 20:(1):80. doi: 10.1186/s12871-020-00992-1
    [Google الباحث العلمي]
  6. Stam J. Thrombosis of the cerebral veins and sinuses. N Engl J Med. 2005; 352:(17):1791–8. doi: 10.1056/NEJMra042354
    [Google الباحث العلمي]
  7. Pabinger I, Grafenhofer H, Kyrle PA, Quehenberger P, Mannhalter C, Lechner K, et al. Temporary increase in the risk for recurrence during pregnancy in women with a history of venous thromboembolism. Blood. 2002; 100:(3):1060–2. doi: 10.1182/blood-2002-01-0149
    [Google الباحث العلمي]
  8. Lanska DJ, Kryscio RJ. Risk factors for peripartum and postpartum stroke and intracranial venous thrombosis. Stroke. 2000; 31:(6):1274–82. doi: 10.1161/01.str.31.6.1274
    [Google الباحث العلمي]
  9. Appenzeller S, Zeller CB, Annichino-Bizzachi JM, Costallat LT, Deus-Silva L, Voetsch B, et al. Cerebral venous thrombosis: influence of risk factors and imaging findings on prognosis. Clin Neurol Neurosurg. 2005; 107:(5):371–8. doi: 10.1016/j.clineuro.2004.10.004
    [Google الباحث العلمي]
  10. Garetier M, Rousset J, Pearson E, Tissot V, Gentric JC, Nowak E, et al. Value of spontaneous hyperdensity of cerebral venous thrombosis on helical CT. Acta Radiol. 2014 Dec; 55:(10):1245–52. doi: 10.1177/0284185113513977
    [Google الباحث العلمي]
  11. Saposnik G, Barinagarrementeria F, Brown RD Jr, , Bushnell CD, Cucchiara B, Cushman M, et al. American Heart Association Stroke Council and the Council on Epidemiology and Prevention. Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2011 Apr; 42:(4):1158–92. doi: 10.1161/STR.0b013e31820a8364
    [Google الباحث العلمي]
  12. Zhang S, Hu Y, Li Z, Huang D, Zhang M, Wang C, et al.. Endovascular treatment for hemorrhagic cerebral venous sinus thrombosis: experience with 9 cases for 3 years. Am J Transl Res. 2018 Jun 15; 10:(6):1611–19. PMID: 30018704
    [Google الباحث العلمي]
  13. Ulivi L, Squitieri M, Cohen H, Cowley P, Werring DJ. Cerebral venous thrombosis: a practical guide. Pract Neurol. 2020 Oct; 20:(5):356–67. doi: 10.1136/practneurol-2019-002415
    [Google الباحث العلمي]
  14. Aaron S, Alexander M, Moorthy RK, Mani S, Mathew V, Patil AK, et al. Decompressive craniectomy in cerebral venous thrombosis: a single centre experience. J Neurol Neurosurg Psychiatry. 2013 Sep; 84:(9):995–1000. doi: 10.1136/jnnp-2012-303356
    [Google الباحث العلمي]
  15. Coutinho JM, Stam J. How to treat cerebral venous and sinus thrombosis. J Thromb Haemost. 2010; 8:(5):877–83. doi: 10.1111/j.1538-7836.2010.03799.x
    [Google الباحث العلمي]
  16. Aguiar de Sousa D, Canhão P, Ferro JM. Safety of pregnancy after cerebral venous thrombosis: a systematic review. Stroke. 2016 Mar; 47:(3):713–18. doi: 10.1161/STROKEAHA.115.011955
    [Google الباحث العلمي]
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  • نوع المستند: Research Article
الموضوعات الرئيسية PregnancyPuerperium and Thrombosis

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