1887
Volume 2007, Issue 2
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

A total of 78,428 blood units collected by the Blood Donor Unit, Hamad Medical Corporation, Doha, from the multinational donors of Qatar (28,622 Qatari nationals donors and 49,806 Non-Qatari donors) in the period January 1994 to Dececember 2001 were screened for hepatitis markers. About 10,382 units (13.2%) were discarded because of positivity for one or more hepatitis markers; 769 units (0.9%) were positive for hepatitis-B surface antigen (HBsAg), 8516 units (10.9%) were positive for hepatitis-B core antibodies (HBcAb) and 1097 units (1.39%) were positive for hepatitis C (HCV) antibodies. There was no significant difference between the rate of positivity for HBcAb and HBsAg in indigenous Qataris and Non-Qataris despite a slightly higher rate ofpositivity for HCV antibodies in the Non-Qatari group. An outstanding finding was the significantly high rate of positivity for HCV antibodies in Egyptian donations (11.2%), which accounted for 31.2% of all discards for the Non-Qatari group. As the Blood Donor Unit at HMC is the only blood collection center in Qatar it is assumed that the results could be representative of the country as a whole.

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2007-11-01
2024-04-18
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References

  1. Regan, Patricia Hewitt, John, A.J. Barbara, Marcella Contreras, Fiona AM. Prospective investigation of transfusion transmitted infection in recipients of over 20 000 units of blood. BMJ. 2000; 320:7232:403406.
    [Google Scholar]
  2. Jay E. Menitove Transfusion-Transmitted Infections: Update. Seminar in Hematology. 1996; 33:4:290301.
    [Google Scholar]
  3. Schreiber GB, Busch MP, Kleinman SH, Korelitz JJ. The risk of transfusion-transmitted viral infections. The Retrovirus Epidemiology Donor Study. N Eng J Med. 1996; 334:26:16851690.
    [Google Scholar]
  4. Chiavetta JA, Escobar M, Newman A, He Y, Driezen P, Deeks S, Hoi DE, O'Brien SE, Sher G. Incidence and estimated rates of residual risk for HIV, hepatitis C, hepatitis B and human T- cell lymphotropic viruses in blood donors in Canada, 1990- 2000. CMAJ. 2003; 169:8:767773.
    [Google Scholar]
  5. Glynn SA, Kleinman SH, Schreiber GB, Busch MP, Wright DJ, Smith JW, Nass CC, Williams AE. Trends in incidence and prevalence of major transfusion-transmissible viral infections in US blood donors, 1991-1996. JAMA. 2000; 248:2:238240.
    [Google Scholar]
  6. Adrian M, Di Bisceglie . Hepatitis C (Seminar). Lancet. 1998; 351::351355.
    [Google Scholar]
  7. Murphy EL, Bryzman S, Williams AE, Co-Chien H, Schreiber GB, Ownby HE, Gilcher RO, Kleinman SH, Matijas L, Thomson RA. Demographic determinants of hepatitis C virus seroprevalence among blood donors. JAMA. 1996; 275:13:9951000.
    [Google Scholar]
  8. Abdelaal M, Rowbottom D, Zawawi T, Scott T, Gilpin C Transfusion. 1994; 34:2:135137.
    [Google Scholar]
  9. Darwish MA, Raouf TA, Rushdy P, Constantine NT, Rao MR, Edeln R. Risk factors associated with a high seroprevalence of hepatitis virus infection in Egyptian blood donors. Am J Trop Med & Hyg. 1993; 49:4:440447.
    [Google Scholar]
  10. Quinti I, Renganathan E, El Ghazzawi E, Divizia M, Sawaf G, Awad Pana A, Rocchi G. Seroprevalence of HIV and HCV infections in Alexandria, Egypt. Zentralbl Bakteriol. 1995; 283:2:239244.
    [Google Scholar]
  11. Nafeh MA, Medhat A, Shehata M, Mikhail NN, Swifee Y, et al., Hepatitis C in a community in Upper Egypt: 1. Crosssectional survey. Am J Trop Med Hyg. 2000; 63:5-6:236241.
    [Google Scholar]
  12. El Zayedi AR, Selim O, Ibrahim EH, Hamdy H, Dabbous H, Ahdy A, Moneim SA. Does schistsomiasis play a role in the high sero-prevalence of HCV antibody among Egyptians? Trop Gastroenterol. 1997; 18:3:98100.
    [Google Scholar]
  13. Darwish MA, Faris R, Clemens JD, Rao MR, Edelman R. High seroprevalence of hepatitis A, B, C and E viruses in residents in an Egyptian village in The Nile Delta: A pilot study. Am J Trop Med Hyg. 1996; 57:3:251.
    [Google Scholar]
  14. Arthur RR, Hassan NF, Abdallah MY, el- Sharkawy MS, Saad MD, Hackbart BG, Imam IZ. Hepatitis C antibody prevalence in blood donors in different governorates in Egypt. Trans R Soc Trop Med Hyg. 1997; 91:3:271284.
    [Google Scholar]
  15. Abdel Wahab MF, Zakaria S, Kamel M, Abdel Khaliq MK, Mabrouk MA, Salama H, Esmat G, Thomas DL, Strickland GT. High seroprevalence of hepatitis C infection among risk groups in Egypt. Am J Trop Med Hyg. 1994; 51:5:563567.
    [Google Scholar]
  16. Kakepoto GN, Bhally HS, Khaliq G, Kayani N, Burney IA, Siddiqui Khurshid M. Epidemiology of blood-borne viruses: A study of healthy blood donors in Southern Pakistan. Southeast Asian J Trop Med Public Health. 1996; 27:4:703706.
    [Google Scholar]
  17. Khattak MF, Salamat N, Bhatti FA, Qureshi TZ. Seroprevalence of hepatitis of hepatitis B, C and HIV in blood donors in northern Pakistan. J Pak Med Assoc. 2002; 52:9:398402.
    [Google Scholar]
  18. Chandrasekaran S, Palaniappan N, Krishnan V, Mohan G, Chandrasekaran N. Relative prevalence of hepatitis B viral markers and hepatitis C virus antibodies (ant-HCV) in Madurai, South India. Indian J Med Sci. 2000; 54:7:270230.
    [Google Scholar]
  19. Jain A, Rana SS, Chakravarty P, Gupta PK, Murthy NS, Nath MC, Gururaja S, Chatturvedi N, Verma U, Kar P. The prevalence of hepatitis C virus antibodies among the voluntary blood donors of New Delhi, India. Eur J Epidemiol. 2003; 18:7:695297.
    [Google Scholar]
  20. Panigrahi AK, Panda SK, Dixit RK, Rao KV, Acharya SK, Dasarath , Nanu A. Magnitude of hepatitis C virus infection in India: prevalence in healthy blood donors, acute and chronic liver disease, med Virol. 1997; 51:3:167174.
    [Google Scholar]
  21. Garag S, Mathur DR, Garg DK. Comparison of seropositivity of HIV, HBV, HCV and syphilis in replacement and voluntary blood donors in western India. Indian J Pathol Microbiol. 2001; 44:4:409412.
    [Google Scholar]
  22. Ghavanini AA, Sabri MR. Hepatitis B surface antigen and anti-hepatitis C antibodies among blood donors in the Islamic Republic of Iran. East Mediterr Health J. 2000; 6:5-6:11141116.
    [Google Scholar]
  23. Albert M Lema, Edmundo A. Cox Hepatitis C Antibodies among Blood Donors in Qatar. Vox Sang. 1992; 63::237.
    [Google Scholar]
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