1887
Volume 2005, Issue 1
  • ISSN: 0253-8253
  • EISSN: 2227-0426

Abstract

Cervical cancer is the third most common cancer worldwide and the leading cause of death from cancer amongst women in developing countries. A study in Qatar in 1997 found that the cancer of the cervix was the most common type of cancer in the female genital tract. In order to further assess the relevance of various risk factors, the records were reviewed of 100 women diagnosed with cervical cancer and intraepithelial lesions between January 2000 and October 2002. There was a highly significant association between detection of human papilloma viruses and increasing incidences of cervical intraepithelial lesions especially with low grade squamous intraepithelial lesions. Young women were more likely to have mostly low grade intraepithelial lesions whereas older women were more likely to have adenocarcinoma and there was a significant relation between parity and risk of the disease. Human papillomaviruses infections, early marriage andfrequent coitus started early in life and an increasing number of pregnancies were predisposing factors for the genesis of cancer of the cervix in Qatar. Older women do not realize that the risk of developing cervical cancer is not reduced as they age and it is important for them to continue having pap smears.

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2005-06-01
2024-03-29
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References

  1. Greenlee RT, Hill-Harmon MB, Murray T, et al., Cancer statistics, CA. A Cancer Journal for Clinicians. 2001; 51:1:1536.
    [Google Scholar]
  2. Al Sakka M, Dauleh W, Hasseh F, Ejeckam G, Abdulla F. Gynecological malignancies in Qatar. Qatar Medical Journal. 1999; 8:2:73.
    [Google Scholar]
  3. Jones WB, Mercer GO, Lewis JL, et al., Early invasive carcinoma of the cervix. Gynecologic Oncology. 1993; 51:1:2632.
    [Google Scholar]
  4. Parazzini F, Chatenoud L, La Vecchia C, Negri E, Franceschi S. Determinants of risk of invasive cervical cancer in young women. Br Cancer. 1998; 77::838841.
    [Google Scholar]
  5. Schairer C, Brinton LA, Devesa SS, et al., Racial differences in the risk of invasive squamous-cell cervical cancer. Cancer Causes and Control. 1991; 2:5:283290.
    [Google Scholar]
  6. Schiffman MH, Bauer HM, Hoover RN, et al., Epidemiologic evidence showing that human papillomavirus infection causes most cervical intraepithelial neoplasia. Journal of the National Cancer Institute. 1993; 85:12:958964.
    [Google Scholar]
  7. Brock KE, MacLennan R, Brinton LA, et al., Smoking and infectious agents and risk of in situ cervical cancer in Sydney, Australia. Cancer Research. 1989; 49:17:49254928.
    [Google Scholar]
  8. Schafer A, Friedmann W, Mielke M, et al., The increased frequency of cervical dysplasia-neoplasia in women infected with the human immunodeficiency virus is related to the degree of immunosuppression. American Journal of Obstetrics and Gynecology. 1991; 164:2:593599.
    [Google Scholar]
  9. Sevin BU, Nadji M, Averette HE. Microinvasive carcinoma of the cervix. Cancer. 1992; 70:8:21212128.
    [Google Scholar]
  10. Brinton LA:. Epidemiology of cervical cancer—overview. I ARC Scientific Publications. 1992; 119::323.
    [Google Scholar]
  11. Wright TC, Gagnon S, Richart RM, et al., Treatment of cervical intraepithelial neoplasia using the loop electro surgical excision procedure. Obstetrics and Gynecology. 1992; 79:2:173178.
    [Google Scholar]
  12. Hatch KD, Schneider A, Abdel-Nour MW. An evaluation of human papillomavirus testing for intermediate and high-risk types as triage before colposcopy. Am J Obstet Gynecology. 1995; 172::11501155.
    [Google Scholar]
  13. Cuzik J, Sasieni P, Singer A. Risk factors for invasive cervix cancer in young women. Eur J Cancer. 1996; 32A::836841.
    [Google Scholar]
  14. Koss LG. Cervical (Pap) smear: new directions. Cancer. 1993; 71:4, Suppl:14061412.
    [Google Scholar]
  15. Bosch FX, Moreno V, Munoz N, et al., for the IARC Multicentric Cervical Cancer Study Group. Oral contraceptive and cervical cancer: a pooled analysis of the IARC multicenter case-control study. Lancet. 2002; 359::10851092.
    [Google Scholar]
  16. Autier P, Coibion M, Huet F, Grivegnee AR. Transformation zone location and intraepithelial neoplasia of the cervix uteri. Br Cancer. 1996; 74::488490, QATAR.
    [Google Scholar]
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