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Volume 2021, Issue 1
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

Lumbosacral spinal stenosis (LSS) is one of the most common causes of back pain and disability. Its treatment varies from surgical to conservative, and the indications for optimal management are not obviously defined. This study aimed to compare the efficacy of caudal epidural injection (CEI) of steroid with and without calcitonin in patients with LSS. This is a randomized, double-blind clinical trial of 31 LSS patients diagnosed between January 1, 2017, to December 30, 2017, who were randomly allocated into two groups. Group A consisted of 17 patients who received C-arm (mobile fluoroscopy)- guided CEI of local anesthetic and steroid, and group B included 14 patients who received C-arm-guided CEI of 100 international unit calcitonin added to local anesthetic and steroid. Outcome measures included the visual analog scale (VAS) for pain during movement and walking distance, Oswestry disability index (ODI), and Quebec back pain disability scale (QBPDS) score, which were obtained from patients before the CEI as a baseline and after the second, fourth, and eighth weeks. Before CEI, no significant differences were found between the two groups, neither in demographic characteristics nor in VAS, ODI, and QBPDS parameters. After CEI, VAS, ODI, and QBPDS improved from baseline through the second, fourth, and eighth weeks in both groups (p < 0.001) without any superiority between the two groups (p = 0.012, 0.078, and 0.019). : CEI of steroid with and without adding calcitonin appears effective in the management of LSS. However, CEI of calcitonin does not appear to have any superiority when compared with steroid injection alone.

© 2021 Farpour, Pirzad, Ahmed, Askarpour, Nikbakht, licensee HBKU Press.
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2021-07-06
2024-04-23
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http://instance.metastore.ingenta.com/content/journals/10.5339/jemtac.2021.7
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Efficacy of caudal epidural injection of steroid versus steroid and calcitonin in patients with lumbosacral spinal stenosis: A randomized clinical trial
Journal of Emergency Medicine, Trauma and Acute Care 2021, 7 (2021); https://doi.org/10.5339/jemtac.2021.7
/content/journals/10.5339/jemtac.2021.7
/content/journals/10.5339/jemtac.2021.7
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Keyword(s): calcitonin, clinical trial, epidural, lumbar, spinal stenosis and steroid

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