@article{hbkup:/content/journals/10.5339/qmj.2019.qccc.60, author = "Akbar, Anzila and Albadw, Naseem and Racela, Brian and Damodaran, Chokkalinga and Mustafa, Emad and Coria, Roopa and Hassan, Ali and Saif Ibrahim, Abdulsalam", title = "Safety of prone positioning in critically ill patients", journal= "Qatar Medical Journal", year = "2020", volume = "2019", number = "2 - Qatar Critical Care Conference Proceedings", pages = "", doi = "https://doi.org/10.5339/qmj.2019.qccc.60", url = "https://www.qscience.com/content/journals/10.5339/qmj.2019.qccc.60", publisher = "Hamad bin Khalifa University Press (HBKU Press)", issn = "2227-0426", type = "Journal Article", keywords = "prone positioning", keywords = "extracorporeal membrane oxygenation", keywords = "acute respiratory distress syndrome", keywords = "hypoxemia", eid = "60", abstract = "Background: During the past two years, 5% of patients admitted to the Medical Intensive Care Unit (MICU) of Hamad General Hospital (HGH) had severe acute respiratory distress syndrome (ARDS) with a PaO2/FiO2 ratio less than 100 mmHg. The risks associated with this condition include ventilator associated lung injury, over distension of lungs, and poor gas exchange which results in increased morbidity and mortality. With quality improvement initiatives like prone positioning, the mortality and morbidity associated with severe acute respiratory syndrome1 can be reduced by improving hypoxemia2 with a significant enhancement in PaO2/FiO2 ratios while reducing injurious ventilation. Also, prone positioning can help prevent invasive interventions such as placing patients on extracorporeal membrane oxygenation (ECMO) therapy.3Methods: We evaluated the safety of prone positioning for improving hypoxemia in critically ill patients with PaO2/FiO2 ratio < 100 mmHg to PaO2/FiO2 ratio < 200 mmHg from 1st January 2017 to 31st December 2018, without major complications. Data collected included the PaO2/FiO2 ratios based on arterial blood gases of mechanically ventilated patients before and after prone positioning. We were able to facilitate prone positioning in 72 out of 110 patients with severe ARDS having a total average PaO2/FiO2 ratio of 84.4 ± 30 mmHg. The patients were proned for a maximum of 16 hours in each session where up to three sessions were incorporated. No major complications were encountered during the proning sessions. This was thought to be accomplished through the coordination of a dedicated multidisciplinary team, education and simulation classes for physicians, nurses, and respiratory therapists, following appropriate inclusion and exclusion criteria for prone positioning, and implementing quality measures through Plan-Do-Study-Act (PDSA) cycles as represented in Figure 1. Results: The total average PaO2/FiO2 ratio before proning for 65% of patients (n = 72) with severe acute respiratory distress syndrome4 was 84.4 ± 30 mmHg and after one hour of 16 hours proning, it improved to 180.3 ± 78 mmHg. The remaining 35% of patients either had traumatic fractures, unstable spinal injury, severe hemodynamic instability, or morbid obesity together with ARDS which made them unfavorable for prone positioning. Out of those who were proned, 11 (12.5%) patients did not have improvement in oxygenation after proning due to non-recruitable lungs and were put on ECMO. The PaO2/FiO2 ratios before and after one hour of implementing the prone position technique in each quarter of 2017 and 2018 are represented in Figure 2. Conclusion: In patients with severe ARDS, prone positioning proves to be a safe practice and leads to improvement in hypoxemia without major complications. Our future prospects with respect to prone positioning include the following: • Sustaining and standardizing the accomplished work of data collection. • Implementing the prone positioning technique across other critical care units of Hamad Medical Corporation. • Keeping a record of minor complications associated with prone positioning and resolving them in further sessions. • Documenting cases with contraindications to prone positioning. ", }