@article{hbkup:/content/journals/10.5339/qmj.2005.2.7, author = "Bel Haj, N. B. and Giaffer, M. H.", title = "Challenges and Controversies in the Management of Hepatitis C Virus Infection (Part 1)", journal= "Qatar Medical Journal", year = "2005", volume = "2005", number = "2", pages = "", doi = "https://doi.org/10.5339/qmj.2005.2.7", url = "https://www.qscience.com/content/journals/10.5339/qmj.2005.2.7", publisher = "Hamad bin Khalifa University Press (HBKU Press)", issn = "2227-0426", type = "Journal Article", eid = "7", abstract = "Hepatitis C virus (HCV) is emerging as a public health issue in most counties worldwide. The prevalence of HCV infection varies among different geographical areas from 0.5% to 40% with an overall global prevalence of 3%. The WHO estimates that around 170 million people are chronically infected with HCV world wide. Hepatitis CV infection causes a slowly progressive liver disease in over 60% of infected individuals culminating into cirrhosis and ultimately leading to liver failure and hepatocellular carcinoma (HCC). Chronic liver disease due to HCV infection is now the leading indication for livertransplantation both in Europe and the USA. Although the incidence of acute hepatitis C has decreased over the last decade, the number of individuals with HCV-related liver disease continues to rise and is projected to peak around year 2015. As such HCV infection imposes a significant burden on the already exhausted health resources, particularly in the developing counties where the infection is endemic and its incidence is increasing.", }