1887
Volume 2000, Issue 2
  • ISSN: 0253-8253
  • E-ISSN: 2227-0426

Abstract

Advances in molecular genetics have now established that Cystic Fibrosis (CF) is due to DNA variations which modify the sequence, structure, function and/or expression of the CF transmembrane conductance regulator (CFTR) gene. To date over 885 such variations have been described. However, worldwide 65% of all CFTR gene mutations are a result of the DF508 mutation.

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/content/journals/10.5339/qmj.2000.2.6
2000-12-01
2019-12-12
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