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Volume 2025, Issue 2
  • ISSN: 1999-7086
  • EISSN: 1999-7094

Abstract

The prognostic ability of the urea-to-albumin ratio (UAR), systemic immune-inflammation index (SII), and neutrophil-to-lymphocyte ratio (NLR) has not yet been assessed in local peritonitis. Therefore, our aim was to determine whether these prognostic tools can predict which patients are at increased risk for fatal outcomes.

A retrospective analysis including 76 patients operated on for local peritonitis in an emergency setting at University Hospital Stara Zagora for the period January 2017–April 2022 was performed. We investigated the prognostic qualities of UAR, SII, and NLR, and then compared them with those of the prognostic scores quick-Sequential Organ Failure Assessment (qSOFA) and World Society of Emergency Surgery Sepsis Severity Score (WSES SSS) by ROC curve analysis.

The established in-hospital mortality was 9.2%. The adverse outcome was successfully predicted by UAR (AUROC = 0.868, = 0.002) and WSES SSS (AUROC = 0.770, = 0.019). NLR (AUROC = 0.704, = 0.077) and SII (AUROC = 0.571, = 0.535) were observed as not helpful prognostic factors, while UAR showed high prognostic performance at an optimal cut-off value = 35.4 with a maximum sensitivity of 100% and a specificity of 77.8%.

A high-risk patient with local peritonitis can be identified quickly and inexpensively using UAR.

© 2025 Dimitrov, Muman, Minkov, Enchev, Yovtchev, licensee HBKU Press.
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2025-03-10
2025-03-26
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/content/journals/10.5339/jemtac.2025.12
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How to identify high-risk patients for fatal outcome due to local peritonitis?—A retrospective analysis
Journal of Emergency Medicine, Trauma and Acute Care 2025, 12 (2025); https://doi.org/10.5339/jemtac.2025.12
/content/journals/10.5339/jemtac.2025.12
/content/journals/10.5339/jemtac.2025.12
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  • Article Type: Research Article
Keyword(s): local peritonitis, mortality, NLR, ratio, SII and UAR

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