%0 Journal Article %A Mayavel, P. %A Thirumurthy, K. %A Dineshkumar, S. %A Thirunarayanan, G. %T Solvent-free synthesis, spectral studies, antimicrobial activities of some (E)-N-(substituted benzylidene)-9-ethyl-9H-carbazole-3-amine derivatives %D 2014 %J QScience Connect, %V 2014 %N 1 %@ 2223-506X %C 11 %R https://doi.org/10.5339/connect.2014.11 %K antimicrobial and antifungal activity %K solvent-free synthesis %K fly-ash:perchloric acid %K IR and NMR spectra %K spectral QSAR study %K aryl imines %I Hamad bin Khalifa University Press (HBKU Press), %X Background: This study aims to synthesis a series of (E)-N-(substituted benzylidene)-9-ethyl-9H-carbazole-3-amines, using solvent-free fly-ash:perchloric acid catalyst under microwave irradiation. To then characterize them using analytical, physical and spectroscopic data. Methods: Solvent-free microwave assisted (E)imines were adopted for the synthesis of (E)-N-(substituted benzylidene)-9-ethyl-9H-carbazole-3-amine, using fly-ash:perchloric acid as a catalyst. They were characterized by IR, NMR and mass spectroscopic data. The IR and NMR spectral data was correlated with substituent constants, F and R parameters using Hammett equation to study the effect of the substituents. Results: The yield of the synthesized imines were more than 75%. The spectral data of these (E)-N-(substituted benzylidene)-9-ethyl-9H-carbazole-3-amines had been correlated using single and multi-regression analysis. These gave a satisfactory or fair degree of correlation, with some parameters. Conclusion: Easy handling, non-hazardous and an environmentally safe method had been adopted for the synthesis of (E)-imines, using fly-ash:perchloric acid as catalyst, with better yields. Some of the Hammett spectral correlations were found to be satisfactory with the observed spectroscopic data. %U https://www.qscience.com/content/journals/10.5339/connect.2014.11